| Literature DB >> 11563124 |
N K Christensen1, J K Dalskov, P Nielsen.
Abstract
Three different synthetic routes to the alpha-configured LNA thymine monomer starting from D-allose or D-arabinose were investigated. The introduction of one or four alpha-LNA monomers into alpha-DNA had a destabilizing effect on the duplexes. However, a fully modified alpha-LNA sequence displayed strong recognition of complementary RNA, but no transition with DNA.Entities:
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Year: 2001 PMID： 11563124 DOI： 10.1081/NCN-100002438
Source DB: PubMed Journal: Nucleosides Nucleotides Nucleic Acids ISSN： 1525-7770 Impact factor: 1.381