Literature DB >> 11563119

A new "native ligation" procedure for peptide-oligonucleotide conjugation.

D A Stetsenko1, M J Gait.   

Abstract

"Native ligation", a powerful method of joining peptide fragments, has been applied successfully to peptide-oligonucleotide conjugation. Novel reagents are described for the solid-phase synthesis of peptide N-terminal thioesters and 5'-cysteinyl oligonucleotides suitable for ligation reactions.

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Year:  2001        PMID: 11563119     DOI: 10.1081/NCN-100002433

Source DB:  PubMed          Journal:  Nucleosides Nucleotides Nucleic Acids        ISSN: 1525-7770            Impact factor:   1.381


  1 in total

1.  Expanding the use of zymography by the chemical linkage of small, defined substrates to the gel matrix.

Authors:  Vladimir R Kaberdin; Kenneth J McDowall
Journal:  Genome Res       Date:  2003-08       Impact factor: 9.043

  1 in total

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