Literature DB >> 11562967

Synthesis of modified nucleoside 5'-triphosphates for in vitro selection of catalytic nucleic acids.

J Matulic-Adamic1, A T Daniher, A Karpeisky, P Haeberli, D Sweedler, L Beigelman.   

Abstract

2'-Modified pyrimidine nucleoside 5'-triphosphates comprising amino, imidazole and carboxylate functionality attached to the 5-position of the base were synthesized. Two different phosphorylation methods were used to optimize the yields of these highly modified triphosphates.

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Year:  2001        PMID: 11562967     DOI: 10.1081/NCN-100002500

Source DB:  PubMed          Journal:  Nucleosides Nucleotides Nucleic Acids        ISSN: 1525-7770            Impact factor:   1.381


  1 in total

1.  Amino-functionalized DNA: the properties of C5-amino-alkyl substituted 2'-deoxyuridines and their application in DNA triplex formation.

Authors:  John A Brazier; Takayuki Shibata; John Townsley; Brian F Taylor; Elaine Frary; Nicholas H Williams; David M Williams
Journal:  Nucleic Acids Res       Date:  2005-03-03       Impact factor: 16.971

  1 in total

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