Literature DB >> 11562504

Mechanisms of pain.

C L Stucky1, M S Gold, X Zhang.   

Abstract

Persistent or chronic pain is the primary reason people seek medical care, yet current therapies are either inadequate for certain types of pain or cause intolerable side effects. Recently, pain neurobiologists have identified a number of cellular and molecular processes that lead to the initiation and maintenance of pain. Understanding these underlying mechanisms has given significant promise for the development of more effective, more specific pain therapies in the near future.

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Year:  2001        PMID: 11562504      PMCID: PMC59728          DOI: 10.1073/pnas.211373398

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  16 in total

Review 1.  Ion channels of nociception.

Authors:  E W McCleskey; M S Gold
Journal:  Annu Rev Physiol       Date:  1999       Impact factor: 19.318

2.  Cholecystokinin and its antagonist lorglumide respectively attenuate and facilitate morphine-induced inhibition of C-fiber evoked discharges of dorsal horn nociceptive neurons.

Authors:  D E Kellstein; D D Price; D J Mayer
Journal:  Brain Res       Date:  1991-02-01       Impact factor: 3.252

3.  The capsaicin receptor: a heat-activated ion channel in the pain pathway.

Authors:  M J Caterina; M A Schumacher; M Tominaga; T A Rosen; J D Levine; D Julius
Journal:  Nature       Date:  1997-10-23       Impact factor: 49.962

4.  Down-regulation of mu-opioid receptors in rat and monkey dorsal root ganglion neurons and spinal cord after peripheral axotomy.

Authors:  X Zhang; L Bao; T J Shi; G Ju; R Elde; T Hökfelt
Journal:  Neuroscience       Date:  1998-01       Impact factor: 3.590

Review 5.  Tackling pain at the source: new ideas about nociceptors.

Authors:  W D Snider; S B McMahon
Journal:  Neuron       Date:  1998-04       Impact factor: 17.173

6.  Effect of morphine on cholecystokinin and mu-opioid receptor-like immunoreactivities in rat spinal dorsal horn neurons after peripheral axotomy and inflammation.

Authors:  X Zhang; G de Araujo Lucas; R Elde; Z Wiesenfeld-Hallin; T Hökfelt
Journal:  Neuroscience       Date:  2000       Impact factor: 3.590

7.  IB4-binding DRG neurons switch from NGF to GDNF dependence in early postnatal life.

Authors:  D C Molliver; D E Wright; M L Leitner; A S Parsadanian; K Doster; D Wen; Q Yan; W D Snider
Journal:  Neuron       Date:  1997-10       Impact factor: 17.173

8.  Isolectin B(4)-positive and -negative nociceptors are functionally distinct.

Authors:  C L Stucky; G R Lewin
Journal:  J Neurosci       Date:  1999-08-01       Impact factor: 6.167

9.  A distinct subgroup of small DRG cells express GDNF receptor components and GDNF is protective for these neurons after nerve injury.

Authors:  D L Bennett; G J Michael; N Ramachandran; J B Munson; S Averill; Q Yan; S B McMahon; J V Priestley
Journal:  J Neurosci       Date:  1998-04-15       Impact factor: 6.167

10.  Immunocytochemical localization of trkA receptors in chemically identified subgroups of adult rat sensory neurons.

Authors:  S Averill; S B McMahon; D O Clary; L F Reichardt; J V Priestley
Journal:  Eur J Neurosci       Date:  1995-07-01       Impact factor: 3.386

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  22 in total

1.  The fundamental unit of pain is the cell.

Authors:  David B Reichling; Paul G Green; Jon D Levine
Journal:  Pain       Date:  2013-12       Impact factor: 6.961

Review 2.  Targeting TRPV1 as an alternative approach to narcotic analgesics to treat chronic pain conditions.

Authors:  Louis S Premkumar
Journal:  AAPS J       Date:  2010-05-04       Impact factor: 4.009

3.  Evaluation of Analgesic and Anti-Inflammatory Activity of Extract of Holoptelea Integrifolia and Argyreia Speciosa in Animal Models.

Authors:  Bhavesh K Lalan; R S Hiray; B B Ghongane
Journal:  J Clin Diagn Res       Date:  2015-07-01

Review 4.  Multimodal analgesia in pain management after spine surgery.

Authors:  Joon S Yoo; Junyoung Ahn; Asokumar Buvanendran; Kern Singh
Journal:  J Spine Surg       Date:  2019-09

5.  The regularity of sustained firing reveals two populations of slowly adapting touch receptors in mouse hairy skin.

Authors:  Scott A Wellnitz; Daine R Lesniak; Gregory J Gerling; Ellen A Lumpkin
Journal:  J Neurophysiol       Date:  2010-04-14       Impact factor: 2.714

Review 6.  Emerging role of Toll-like receptors in the control of pain and itch.

Authors:  Tong Liu; Yong-Jing Gao; Ru-Rong Ji
Journal:  Neurosci Bull       Date:  2012-04       Impact factor: 5.203

Review 7.  Cancer-Induced Bone Pain Management Through Buddhist Beliefs.

Authors:  Fung Kei Cheng
Journal:  J Relig Health       Date:  2017-12

8.  Effect of the antidepressant nefazodone on the density of cells expressing mu-opioid receptors in discrete brain areas processing sensory and affective dimensions of pain.

Authors:  Antonio Ortega-Alvaro; Ignacio Acebes; Gonzalo Saracíbar; Enrique Echevarría; Luis Casis; Juan Antonio Micó
Journal:  Psychopharmacology (Berl)       Date:  2004-04-27       Impact factor: 4.530

Review 9.  Peripheral and central sensitization in fibromyalgia: pathogenetic role.

Authors:  Roland Staud; Michael L Smitherman
Journal:  Curr Pain Headache Rep       Date:  2002-08

Review 10.  Analgesia for patients with advanced disease: I.

Authors:  E J Hall; N P Sykes
Journal:  Postgrad Med J       Date:  2004-03       Impact factor: 2.401

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