Literature DB >> 11560374

Deacetylravidomycin M, a new inhibitor of IL-4 signal transduction, produced by Streptomyces sp. WK-6326. II. Structure elucidation.

M Arai1, H Tomoda, N Tabata, N Ishiguro, S Kobayashi, S Omura.   

Abstract

The structure of deacetylravidomycin M, an inhibitor of interleukin-4 signal transduction, was elucidated to be 6H-benzo[d]naphtho[1,2-b]pyran-6-one, 4-[3,6-dideoxy-3-(dimethylamino)-alpha-altropyranosyl]-1-hydroxy-10,12-dimethoxy-8-methyl- by spectroscopic studies including NMR measurements.

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Year:  2001        PMID: 11560374     DOI: 10.7164/antibiotics.54.562

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  2 in total

Review 1.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

2.  Inactivation of the ketoreductase gilU gene of the gilvocarcin biosynthetic gene cluster yields new analogues with partly improved biological activity.

Authors:  Tao Liu; Madan K Kharel; Lili Zhu; Samuel A Bright; Cynthia Mattingly; Val R Adams; Jürgen Rohr
Journal:  Chembiochem       Date:  2009-01-26       Impact factor: 3.164

  2 in total

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