| Literature DB >> 11558988 |
C P Bleeker1, R C Bremer, D A Dongelmans, R T van Dongen, B J Crul.
Abstract
Pain partially responsive to opioids can lead to rapid escalating dosages due to tolerance development. In this report the case of a 58-year-old female with neuropathic pain using increasing transdermal (TTS) fentanyl dosages to a maximum dose of 3400 microg/h resulting in fentanyl plasma levels of 173 ng/ml is described. For pain relief an epidural infusion at the level T1-2 with bupivacaine was started. Immediate pain relief was accompanied by short lasting respiratory depression and drowsiness. Copyright 2001 European Federation of Chapters of the International Association for the study of Pain.Entities:
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Year: 2001 PMID: 11558988 DOI: 10.1053/eujp.2000.0220
Source DB: PubMed Journal: Eur J Pain ISSN: 1090-3801 Impact factor: 3.931