Literature DB >> 11558982

Computer-controlled pneumatic pressure algometry--a new technique for quantitative sensory testing.

R Polianskis1, T Graven-Nielsen, L Arendt-Nielsen.   

Abstract

Hand-held pressure algometry usually assesses pressure-pain detection thresholds and provides little information on pressure-pain stimulus-response function. In this article, a cuff pressure algometry for advanced pressure-pain function evaluation is proposed. The experimental set-up consisted of a pneumatic tourniquet cuff, a computer-controlled air compressor and an electronic visual analogue scale (VAS) for constant pain intensity rating. Twelve healthy volunteers were included in the study. In the first part, hand-held algometry and cuff algometry were performed over the gastrocnemius muscle with constant compression rate. In the second part, the cuff algometry was performed with different compression rates to evaluate the influence of the compression rate on pain thresholds and other psychophysical data. Pressure-pain detection threshold (PDT), pain tolerance threshold (PTT), pain intensity, PDT-PTT time and other psychophysical variables were evaluated.Pressure-pain detection thresholds recorded over the gastrocnemius muscle with a hand-held and with a cuff algometer, were 482 +/- 19 kPa and 26 +/- 1.6 kPa, respectively. Pressure and pain intensities were correlated during cuff algometry. During increasing cuff compression, the subjective pain tolerance limit on VAS was 5.6 +/- 0.95 cm. There was a direct correlation between the number of compressions, the compression rate and pain thresholds. The cuff algometry technique is appropriate for pressure-pain stimulus-response studies. Cuff algometry allowed quantification of psychophysical response to the change of stimulus configuration. Copyright 2001 European Federation of Chapters of the International Association for the Study of Pain.

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Year:  2001        PMID: 11558982     DOI: 10.1053/eujp.2001.0245

Source DB:  PubMed          Journal:  Eur J Pain        ISSN: 1090-3801            Impact factor:   3.931


  24 in total

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2.  The lateral prefrontal cortex mediates the hyperalgesic effects of negative cognitions in chronic pain patients.

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3.  Translational and Early Phase Strategies for Treatment Development: Report of ISCTM Autumn 2013 Symposium.

Authors:  Jared W Young; William Z Potter; Steve Riley; Geert J Groeneveld; Bruce J Kinon; Mike F Egan; Douglas E Feltner
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4.  Pharmacokinetics and pharmacodynamics of intrathecally administered Xen2174, a synthetic conopeptide with norepinephrine reuptake inhibitor and analgesic properties.

Authors:  Pieter Okkerse; Justin L Hay; Elske Sitsen; Albert Dahan; Erica Klaassen; William Houghton; Geert Jan Groeneveld
Journal:  Br J Clin Pharmacol       Date:  2016-12-16       Impact factor: 4.335

5.  Characterization of Source-Localized EEG Activity During Sustained Deep-Tissue Pain.

Authors:  Juan Manuel Völker; Federico Gabriel Arguissain; José Biurrun Manresa; Ole Kæseler Andersen
Journal:  Brain Topogr       Date:  2021-01-05       Impact factor: 3.020

6.  Does mutual compensation of the cognitive effects induced by pain and opioids exist? An experimental study.

Authors:  Geana Paula Kurita; Lasse Paludan Malver; Trine Andresen; Romanas Polianskis; Asbjørn Mohr Drewes; Lona Christrup; Jette Højsted; Per Sjøgren
Journal:  Psychopharmacology (Berl)       Date:  2014-10-28       Impact factor: 4.530

7.  Different effects of morphine and oxycodone in experimentally evoked hyperalgesia: a human translational study.

Authors:  Anne Estrup Olesen; Camilla Staahl; Lars Arendt-Nielsen; Asbjørn Mohr Drewes
Journal:  Br J Clin Pharmacol       Date:  2010-08       Impact factor: 4.335

8.  The use of a battery of pain models to detect analgesic properties of compounds: a two-part four-way crossover study.

Authors:  Pieter Okkerse; Guido van Amerongen; Marieke L de Kam; Jasper Stevens; Richard P Butt; Rachel Gurrell; Albert Dahan; Joop M van Gerven; Justin L Hay; Geert Jan Groeneveld
Journal:  Br J Clin Pharmacol       Date:  2017-01-09       Impact factor: 4.335

Review 9.  Peripheral and central sensitization in musculoskeletal pain disorders: an experimental approach.

Authors:  Thomas Graven-Nielsen; Lars Arendt-Nielsen
Journal:  Curr Rheumatol Rep       Date:  2002-08       Impact factor: 4.592

10.  Volunteers with high versus low alpha EEG have different pain-EEG relationship: a human experimental study.

Authors:  Line Lindhardt Egsgaard; Li Wang; Lars Arendt-Nielsen
Journal:  Exp Brain Res       Date:  2008-11-15       Impact factor: 1.972

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