Literature DB >> 11558068

[Schoenlein-Henoch purpura in adulthood (gastrointestinal manifestation and endoscopy)].

J Novák1, J Márki-Zay, Z Csiki, J Sebesi, A Takáts, S Sipka.   

Abstract

During a 15-year-period 62 adult patients were admitted with diagnosis of Schoenlein-Henoch purpura in our hospital. 25 female and 37 male patients ranged from 30-87 years (mean: 59.5 years) presenting with cutaneous, joint, renal and particularly abdominal involvement were investigated retrospectively. During the course of the disease, all patients developed purpuric rash (100 %), 14 (22,5 %) patients had joint symptoms and renal involvement occurred in 12 (19,3 %) patients. In this study, we discuss 15 (24 %) patients with gastrointestinal symptoms appearing in Henoch's purpura. Analysis of the gastrointestinal clinical features revealed: Abdominal pain 13 (86 %), massive colorectal bleeding 3 (20 %), occult blood loss 10 (66 %) vomiting 6 (40 %) and diarrhea in 3 (20 %) patients. Surgical consultation was obtained for 4 of the 15 patients and laparotomy was performed in 2 patients. All the patients underwent lower and upper endoscopic examination, in 3 cases the authors saw purpuric mucosal lesions in duodenum and in 8 patients were also found coin-like elevated lesions, additionally, biopsy from colonic lesions showed leukocytoclastic vasculitis. It is concluded that endoscopy may play a very important role in the diagnosis and treatment of Schoenlein-Henoch purpura.

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Year:  2001        PMID: 11558068     DOI: 10.1055/s-2001-17195

Source DB:  PubMed          Journal:  Z Gastroenterol        ISSN: 0044-2771            Impact factor:   2.000


  5 in total

1.  Clostridium difficile Infection and Inflammatory Bowel Disease.

Authors:  David Binion
Journal:  Gastroenterol Hepatol (N Y)       Date:  2016-05

2.  Henoch-Schonlein Purpura With Gastrointestinal Involvement in an Adult Patient.

Authors:  Dharmesh Kaswala; Ari Chodos; Sushil Ahlawat
Journal:  Gastroenterol Hepatol (N Y)       Date:  2016-05

3.  Henoch Schönlein purpura associated with pulmonary adenocarcinoma.

Authors:  Daiki Mifune; Satoshi Watanabe; Rie Kondo; Yoko Wada; Hiroshi Moriyama; Hiroshi Kagamu; Hirohisa Yoshizawa; Takafumi Tetsuka; Asako Matsuyama; Kaoru Ito; Ichiei Narita
Journal:  J Med Case Rep       Date:  2011-06-22

4.  Gastrointestinal involvement revealing Henoch Schonlein purpura in adults: Report of three cases and review of the literature.

Authors:  Amira Hamzaoui; Wissem Melki; Olfa Harzallah; Leila Njim; Rim Klii; Silvia Mahjoub
Journal:  Int Arch Med       Date:  2011-09-29

5.  Henoch-Schonlein Purpura Presenting as Upper Gastrointestinal Bleed in an Adult Patient.

Authors:  Yasmin Khader; Cameron Burmeister; Dipen Patel; Amala Ambati; Nezam Altorok
Journal:  Cureus       Date:  2021-03-14
  5 in total

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