Literature DB >> 11557502

Two new point mutations at A2062 associated with resistance to 16-membered macrolide antibiotics in mutant strains of Mycoplasma hominis.

P M Furneri1, G Rappazzo, M P Musumarra, P Di Pietro, L S Catania, L S Roccasalva.   

Abstract

We describe two mutants of Mycoplasma hominis PG-21 which show resistance to 16-membered macrolides but susceptibility to lincosamides, obtained by in vitro exposure to increasing doses of josamycin. The 23S rRNA gene showed that each had a mutation (A2062G and A2062T) corresponding to nucleotide 2062 in Escherichia coli, which was associated with the acquired phenotype.

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Year:  2001        PMID： 11557502      PMCID： PMC90764          DOI： 10.1128/AAC.45.10.2958-2960.2001

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  33 in total

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Authors:  B Weisblum
Journal:  Antimicrob Agents Chemother       Date:  1995-03       Impact factor: 5.191

Review 2.  Insights into erythromycin action from studies of its activity as inducer of resistance.

Authors:  B Weisblum
Journal:  Antimicrob Agents Chemother       Date:  1995-04       Impact factor: 5.191

3.  Fine structure of the peptidyl transferase centre on 23 S-like rRNAs deduced from chemical probing of antibiotic-ribosome complexes.

Authors:  C Rodriguez-Fonseca; R Amils; R A Garrett
Journal:  J Mol Biol       Date:  1995-03-24       Impact factor: 5.469

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Authors:  S Douthwaite; C Aagaard
Journal:  J Mol Biol       Date:  1993-08-05       Impact factor: 5.469

5.  Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori.

Authors:  J Versalovic; D Shortridge; K Kibler; M V Griffy; J Beyer; R K Flamm; S K Tanaka; D Y Graham; M F Go
Journal:  Antimicrob Agents Chemother       Date:  1996-02       Impact factor: 5.191

6.  Chemical probing of a virginiamycin M-promoted conformational change of the peptidyl-transferase domain.

Authors:  P Vannuffel; M Di Giambattista; C Cocito
Journal:  Nucleic Acids Res       Date:  1994-10-25       Impact factor: 16.971

7.  Functional interactions within 23S rRNA involving the peptidyltransferase center.

Authors:  S Douthwaite
Journal:  J Bacteriol       Date:  1992-02       Impact factor: 3.490

8.  Anti-mycoplasmal activity of a new macrolide: miocamycin.

Authors:  P M Furneri; G Tempera; G Bisignano; F V Cottarelli; G Nicoletti
Journal:  Chemioterapia       Date:  1987-10

9.  Transition mutations in the 23S rRNA of erythromycin-resistant isolates of Mycoplasma pneumoniae.

Authors:  T S Lucier; K Heitzman; S K Liu; P C Hu
Journal:  Antimicrob Agents Chemother       Date:  1995-12       Impact factor: 5.191

10.  Susceptibility of genital mycoplasmas to antimicrobial agents.

Authors:  P Braun; J O Klein; E H Kass
Journal:  Appl Microbiol       Date:  1970-01
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  9 in total

1.  Mutational analysis of 16S and 23S rRNA genes of Thermus thermophilus.

Authors:  Steven T Gregory; Jennifer F Carr; Daniel Rodriguez-Correa; Albert E Dahlberg
Journal:  J Bacteriol       Date:  2005-07       Impact factor: 3.490

2.  Detection and Evaluation of Macrolide Resistance (Erythromycin) in Mycoplasma hominis Isolated from Endocervical Specimens of Patients Referring to Ibn Sina Infertility Treatment Centre, Tehran, Iran.

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3.  Mutations in 23S rRNA account for intrinsic resistance to macrolides in Mycoplasma hominis and Mycoplasma fermentans and for acquired resistance to macrolides in M. hominis.

Authors:  S Pereyre; P Gonzalez; B De Barbeyrac; A Darnige; H Renaudin; A Charron; S Raherison; C Bébéar; C M Bébéar
Journal:  Antimicrob Agents Chemother       Date:  2002-10       Impact factor: 5.191

4.  Epidemiology of Ureaplasma urealyticum and Mycoplasma hominis in the semen of male outpatients with reproductive disorders.

Authors:  Xiaofei Zhu; Min Li; Huiling Cao; Xuewen Yang; Chunbing Zhang
Journal:  Exp Ther Med       Date:  2016-05-31       Impact factor: 2.447

Review 5.  Resistance to macrolide, lincosamide, streptogramin, ketolide, and oxazolidinone antibiotics.

Authors:  Marilyn C Roberts
Journal:  Mol Biotechnol       Date:  2004-09       Impact factor: 2.695

6.  In vitro selection and characterization of resistance to macrolides and related antibiotics in Mycoplasma pneumoniae.

Authors:  S Pereyre; C Guyot; H Renaudin; A Charron; C Bébéar; C M Bébéar
Journal:  Antimicrob Agents Chemother       Date:  2004-02       Impact factor: 5.191

7.  Prevalence of macrolide and fluoroquinolone resistance-mediating mutations in Mycoplasma genitalium in five cities in Russia and Estonia.

Authors:  Elena Shipitsyna; Tatiana Rumyantseva; Daniel Golparian; Guzel Khayrullina; Amaya C Lagos; Inna Edelstein; Kai Joers; Jörgen S Jensen; Alevtina Savicheva; Natalia Rudneva; Larisa Sukhanova; Roman Kozlov; Alexander Guschin; Magnus Unemo
Journal:  PLoS One       Date:  2017-04-13       Impact factor: 3.240

8.  Cryo-EM structure of Mycobacterium tuberculosis 50S ribosomal subunit bound with clarithromycin reveals dynamic and specific interactions with macrolides.

Authors:  Wen Zhang; ZhiFei Li; Yufan Sun; Peng Cui; Jianhua Liang; Qinghe Xing; Jing Wu; Yanhui Xu; Wenhong Zhang; Ying Zhang; Lin He; Ning Gao
Journal:  Emerg Microbes Infect       Date:  2022-12       Impact factor: 7.163

9.  Treatment efficacy, treatment failures and selection of macrolide resistance in patients with high load of Mycoplasma genitalium during treatment of male urethritis with josamycin.

Authors:  Alexander Guschin; Pavel Ryzhikh; Tatiana Rumyantseva; Mikhail Gomberg; Magnus Unemo
Journal:  BMC Infect Dis       Date:  2015-02-03       Impact factor: 3.090
  9 in total

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