| Literature DB >> 11556736 |
H Tanaka1, S Waga, T Nakahata, K Suzuki, T Ito, N Onodera, S Iwami, N Monma, E Ito.
Abstract
Two Japanese sisters with persistent uveitis showed significant increased levels of urinary beta-2 microglobulin. A percutaneous renal biopsy performed in the younger sister revealed tubulointerstitial nephritis (TIN) with helper/inducer T cell infiltrates. Also, abnormal 67-gallium accumulation in the kidneys, suggesting TIN, was observed in the other one at the same time. Although patients with the syndrome of tubulointerstitial nephritis and uveitis (TINU) have been reported to date, its occurrence in siblings has rarely been seen. Both of them shared same human leukocyte antigen (HLA) DR6, suggesting the potential association between HLA-DR6 and TINU.Entities:
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Year: 2001 PMID： 11556736 DOI： 10.1620/tjem.194.71
Source DB: PubMed Journal: Tohoku J Exp Med ISSN： 0040-8727 Impact factor: 1.848