| Literature DB >> 11556674 |
A Stefanovska1, D G Luchinsky, P V McClintock.
Abstract
A mathematical model of the cardiovascular system is simulated numerically. The basic unit in the model is an oscillator that possesses a structural stability and robustness motivated by physiological understanding and by the analysis of measured time series. Oscillators with linear couplings are found to reproduce the main characteristic features of the experimentally obtained spectra. To explain the variability of cardiac and respiratory frequencies, however, it is essential to take into account the rest of the system, i.e. to consider the effect of noise. It is found that the addition of noise also results in epochs of synchronization, as observed experimentally. Preliminary analysis suggests that there is a mixture of linear and parametric couplings, but that the linear coupling seems to dominate.Mesh:
Year: 2001 PMID: 11556674 DOI: 10.1088/0967-3334/22/3/312
Source DB: PubMed Journal: Physiol Meas ISSN: 0967-3334 Impact factor: 2.833