Amniotic fluid glucose: a maternal, fetal, and neonatal correlation.

While it has been noted that amniotic fluid glucose is increased in patients withdiabetes mellitus, the exact significance of this finding is not known. Our study of amniotic fluid glucose in 53 amniotic fluid samples from 41 patients shows a high correlation of amniotic fluid glucose levels of 30 mg. per 100 ml. or greater with neonatal hypoglycemia. We have also found elevated amniotic fluid glucose levels in patients whose onlyother indication of abnormal glucose metabolism was recurrent glycosuria. Thepossible significance of these findings is discussed.