| Literature DB >> 11554830 |
D A Evans1, K A Scheidt, C W Downey.
Abstract
The synthesis of (-)-epibatidine has been accomplished utilizing a highly exo-selective asymmetric hetero Diels-Alder reaction. The key steps employed to transform the resulting bicycle into the natural product include a fluoride-promoted fragmentation and a Hofmann rearrangement. Reaction: see text.Entities:
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Year: 2001 PMID： 11554830 DOI： 10.1021/ol016420q
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005