Literature DB >> 11554437

Autoradiography in brain of Macaca fascicularis monkeys after injection of acetyl-DL-leucine [2-14C] (Tanganil).

P Benard1, H Cousse, T Bengone, C Germain.   

Abstract

Acetyl-DL-leucine [2-14C]: Tanganil a antivertigal drug has been injected intravenously in two macaca monkeys which have been sacrificed 2 and 5 minutes later. Radioactivity distribution has been studied by autoradiography in the brain. An important uptake of radioactivity is localized in the cortical structures and in several tisses such as nuclei of the vestibular system, including the inner ear.

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Year:  2001        PMID： 11554437     DOI： 10.1007/BF03190379

Source DB:  PubMed          Journal:  Eur J Drug Metab Pharmacokinet        ISSN： 0378-7966            Impact factor:   2.441


  9 in total

1.  [Trial therapy of labyrinthine vertigo by acetyl-DL-leucine].

Authors:  J CELICE; O LEAU; R DUCROT; G DUCHESNAY
Journal:  Therapie       Date:  1958       Impact factor: 2.070

2.  [Action of acetylleucine on experimental vertigo in mice].

Authors:  O LEAU; R DUCROT
Journal:  C R Seances Soc Biol Fil       Date:  1957

3.  Studies on the distribution and fate of S35-labelled benzylpenicillin in the body.

Authors:  S ULLBERG
Journal:  Acta Radiol Suppl       Date:  1954

4.  In vitro effects of acetyl-DL-leucine (tanganil) on central vestibular neurons and vestibulo-ocular networks of the guinea-pig.

Authors:  N Vibert; P P Vidal
Journal:  Eur J Neurosci       Date:  2001-02       Impact factor: 3.386

5.  Perspectives on the pharmacotherapy of vertigo.

Authors:  D S Zee
Journal:  Arch Otolaryngol       Date:  1985-09

6.  [Drug therapy of vertigo].

Authors:  O Rascol; J L Montastruc
Journal:  Rev Prat       Date:  1994-02-01

7.  Velocity storage, nystagmus, and visual-vestibular interactions in humans.

Authors:  B Cohen; V Henn; T Raphan; D Dennett
Journal:  Ann N Y Acad Sci       Date:  1981       Impact factor: 5.691

8.  The dizzy patient. Symptomatic treatment of vertigo.

Authors:  R W Baloh
Journal:  Postgrad Med       Date:  1983-05       Impact factor: 3.840

9.  Amino acid profiles in inner ear fluids and cerebrospinal fluid.

Authors:  R Thalmann; T H Comegys; I Thalmann
Journal:  Laryngoscope       Date:  1982-03       Impact factor: 3.325
  9 in total
  2 in total

1.  Beneficial Effects of Acetyl-DL-Leucine (ADLL) in a Mouse Model of Sandhoff Disease.

Authors:  Ecem Kaya; David A Smith; Claire Smith; Barry Boland; Michael Strupp; Frances M Platt
Journal:  J Clin Med       Date:  2020-04-08       Impact factor: 4.964

2.  Acetylation turns leucine into a drug by membrane transporter switching.

Authors:  Grant C Churchill; Michael Strupp; Cailley Factor; Tatiana Bremova-Ertl; Mallory Factor; Marc C Patterson; Frances M Platt; Antony Galione
Journal:  Sci Rep       Date:  2021-08-04       Impact factor: 4.379
  2 in total

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