W Buhre1, K Buhre, S Kazmaier, H Sonntag, A Weyland. 1. Klinik für Anaesthesiologie, Medizinische Fakultät, Rheinisch Westfälische Technische Hochschule Aachen, Pauwelstrasse 30, 5204 Aachen, Germany.
Abstract
BACKGROUND AND OBJECTIVE: Assessment of cardiac preload is of major importance in the management of critically ill patients. Echocardiographic determined left ventricular end-diastolic area and indicator dilution derived intrathoracic blood volume are used as surrogates for cardiac preload. However, no controlled comparison studies on the relationship between induced changes in end-diastolic area and intrathoracic blood volume and concomitant changes in stroke volume index are available. METHODS: The effects of a change in body position on these variables were investigated in 10 anaesthetized patients. RESULTS: Intrathoracic blood volume and end-diastolic area decreased by 18 +/- 11% and 27 +/- 13% respectively. Stroke volume index concomitantly decreased by 19 +/- 11%. Correlation analysis revealed a close relation between stroke volume index and intrathoracic blood volume (r=0.75) and end-diastolic area (r=0.76). CONCLUSIONS: Within the observed range of data, intrathoracic blood volume and end-diastolic area are equivalent indices of cardiac preload.
BACKGROUND AND OBJECTIVE: Assessment of cardiac preload is of major importance in the management of critically illpatients. Echocardiographic determined left ventricular end-diastolic area and indicator dilution derived intrathoracic blood volume are used as surrogates for cardiac preload. However, no controlled comparison studies on the relationship between induced changes in end-diastolic area and intrathoracic blood volume and concomitant changes in stroke volume index are available. METHODS: The effects of a change in body position on these variables were investigated in 10 anaesthetized patients. RESULTS: Intrathoracic blood volume and end-diastolic area decreased by 18 +/- 11% and 27 +/- 13% respectively. Stroke volume index concomitantly decreased by 19 +/- 11%. Correlation analysis revealed a close relation between stroke volume index and intrathoracic blood volume (r=0.75) and end-diastolic area (r=0.76). CONCLUSIONS: Within the observed range of data, intrathoracic blood volume and end-diastolic area are equivalent indices of cardiac preload.
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