Literature DB >> 1155301

The evaluation of cotton twine as a new anti-inflammatory assay.

C L Rassaert, G Dipasquale, S O'Donoghue.   

Abstract

A new anti-inflammatory assay is described, utilizing a subcutaneously implanted elongated section of cotton twine to induce granuloma in rats. The cotton twine irritant is easily introduced under the abdominal skin and after seven days a well formed granuloma is established. The procedure works effectively for both steroidal and non-steroidal anti-inflammatory drug evaluation. Consistency of the cotton twine eliminates individual weighing of each section and uniformity in compactness affords reproducible results.

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Year:  1975        PMID： 1155301     DOI： 10.1007/bf02027353

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  18 in total

1.  COMPARISON OF ANTI-GRANULOMA, THYMOLYTIC AND GLUCOCORTICOID ACTIVITIES OF ANTI-INFLAMMATORY STEROIDS.

Authors:  L J LERNER; A R TURKHEIMER; A BIANCHI; F M SINGER; A BORMAN
Journal:  Proc Soc Exp Biol Med       Date:  1964-06

2.  ANTI-INFLAMMATORY ACTIVITY ON NONSTEROIDAL AGENTS IN A RAT GRANULOMA ASSAY.

Authors:  R I DORFMAN; A S DORFMAN
Journal:  Proc Soc Exp Biol Med       Date:  1965-07

3.  EFFECT OF BODY WEIGHT CHANGES ON THE FORMATION OF COTTON PELLET-INDUCED GRANULOMA.

Authors:  G DIPASQUALE; A MELI
Journal:  J Pharm Pharmacol       Date:  1965-06       Impact factor: 3.765

4.  ANTI-INFLAMMATORY AND ANTIPYRETIC PROPERTIES OF N-(2,6-DICHLORO-M-TOLYL)ANTHRANILIC ACID (CI-583).

Authors:  C V WINDER; J WAX; M WELFORD
Journal:  J Pharmacol Exp Ther       Date:  1965-06       Impact factor: 4.030

5.  The antiinflammatory activity of glycyrrhetinic acid and derivatives.

Authors:  R S FINNEY; G F SOMERS
Journal:  J Pharm Pharmacol       Date:  1958-10       Impact factor: 3.765

6.  The biology of anti-inflammatory steroids.

Authors:  R H SILBER
Journal:  Ann N Y Acad Sci       Date:  1959-10-14       Impact factor: 5.691

7.  Anti-inflammatory activity of delta1-9alpha-fluorohydrocortisone acetate.

Authors:  W E DULIN
Journal:  Proc Soc Exp Biol Med       Date:  1955-10

8.  Effect of pregnancy and lactation on granuloma tissue formation and joint permeability in rats.

Authors:  R K MEYER; J C STUCKI; K A AULSEBROOK
Journal:  Proc Soc Exp Biol Med       Date:  1953-12

9.  [On the mechanism of cortisone inhibition of connective tissue proliferation].

Authors:  R MEIER; W SCHULER; P DESAULLES
Journal:  Experientia       Date:  1950-12-15

10.  Anti-inflammatory, antipyretic and antinociceptive properties of N-(2,3-xylyl)anthranilic acid (mefenamic acid).

Authors:  C V WINDER; J WAX; L SCOTTI; R A SCHERRER; E M JONES; F W SHORT
Journal:  J Pharmacol Exp Ther       Date:  1962-12       Impact factor: 4.030
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  3 in total

1.  Characterization of the Foreign Body Response to Common Surgical Biomaterials in a Murine Model.

Authors:  Mohamed Ibrahim; Jennifer Bond; Manuel A Medina; Lei Chen; Carlos Quiles; George Kokosis; Latif Bashirov; Bruce Klitzman; Howard Levinson
Journal:  Eur J Plast Surg       Date:  2017-04-28

2.  Induction of aneurysms in the rat by a stenosing cotton ligature around the inter-renal aorta.

Authors:  M J Osborne-Pellegrin; M Coutard; P Poitevin; J B Michel; B I Levy
Journal:  Int J Exp Pathol       Date:  1994-06       Impact factor: 1.925

3.  Antiinflammatory activity: evaluation of a new screening procedure.

Authors:  J J Loux; S Smith; H Salem
Journal:  Inflammation       Date:  1977-06       Impact factor: 4.092
  3 in total

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