Literature DB >> 11552282

Thymic carcinoids in multiple endocrine neoplasia-type 1.

S Hirai1, Y Hamanaka, N Mitsui, H Kumagai, T Kobayashi.   

Abstract

We report a case of a 45-year-old man with thymic carcinoids in multiple endocrine neoplasm-type 1. Extended total thymectomy was performed through a median sternotomy, and the mediastinal regional lymph nodes and fibroadipose tissue were dissected. Multiple endocrine neoplasm-type 1 related thymic carcinoids are rare and have a poor prognosis. The efficacy of radiotherapy and chemotherapy for prolonging survival is limited, and an aggressive surgical approach with complete excision of the tumor with resection of the peripheral tissues and dissection of the mediastinal lymph nodes seems to be the best available treatment today. We have found that this practice of thymectomy at an early stage in combination with genetic and effective radiological treatment can be effective for multiple endocrine neoplasm-type 1 patients.

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Year:  2001        PMID: 11552282     DOI: 10.1007/bf02919551

Source DB:  PubMed          Journal:  Jpn J Thorac Cardiovasc Surg        ISSN: 1344-4964


  9 in total

Review 1.  Carcinoid tumors of the thymus.

Authors:  G C Economopoulos; J W Lewis; M W Lee; N A Silverman
Journal:  Ann Thorac Surg       Date:  1990-07       Impact factor: 4.330

2.  Mediastinal endocrine neoplasm, of probable thymic origin, related to carcinoid tumor. Clinicopathologic study of 8 cases.

Authors:  J Rosai; E Higa
Journal:  Cancer       Date:  1972-04       Impact factor: 6.860

3.  Thymic neuroendocrine tumor (thymic carcinoid): a clinicopathologic study in 15 patients.

Authors:  I Fukai; A Masaoka; Y Fujii; Y Yamakawa; T Yokoyama; T Murase; T Eimoto
Journal:  Ann Thorac Surg       Date:  1999-01       Impact factor: 4.330

4.  Clinicopathologic studies of thymic carcinoids in multiple endocrine neoplasia type 1.

Authors:  B T Teh; J McArdle; S P Chan; J Menon; L Hartley; P Pullan; J Ho; A Khir; S Wilkinson; C Larsson; D Cameron; J Shepherd
Journal:  Medicine (Baltimore)       Date:  1997-01       Impact factor: 1.889

5.  Spindle-cell thymic carcinoid occurring in multiple endocrine neoplasia I: fine-needle aspiration findings in a case.

Authors:  D Dusenbery
Journal:  Diagn Cytopathol       Date:  1996-12       Impact factor: 1.582

6.  Carcinoid tumours of the thymus.

Authors:  D Y Wang; D B Chang; S H Kuo; P C Yang; Y C Lee; H C Hsu; K T Luh
Journal:  Thorax       Date:  1994-04       Impact factor: 9.139

Review 7.  The variable penetrance and spectrum of manifestations of multiple endocrine neoplasia type 1.

Authors:  S E Carty; A K Helm; J A Amico; M R Clarke; T P Foley; C G Watson; J J Mulvihill
Journal:  Surgery       Date:  1998-12       Impact factor: 3.982

8.  Thymic neuroendocrine carcinoma (carcinoid): a clinicopathologic study of fourteen cases.

Authors:  V T de Montpréville; P Macchiarini; E Dulmet
Journal:  J Thorac Cardiovasc Surg       Date:  1996-01       Impact factor: 5.209

9.  Thymic carcinoids in multiple endocrine neoplasia type 1.

Authors:  B T Teh; J Zedenius; S Kytölä; B Skogseid; J Trotter; H Choplin; S Twigg; F Farnebo; S Giraud; D Cameron; B Robinson; A Calender; C Larsson; P Salmela
Journal:  Ann Surg       Date:  1998-07       Impact factor: 12.969

  9 in total
  1 in total

Review 1.  Multiple endocrine neoplasia type I.

Authors:  Rasa Zarnegar; Laurent Brunaud; Orlo H Clark
Journal:  Curr Treat Options Oncol       Date:  2002-08
  1 in total

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