Literature DB >> 11552087

Pharmacologic modulation of fetal hemoglobin.

M H Steinberg1, G P Rodgers.   

Abstract

Mesh：

Substances：

Year:  2001        PMID： 11552087     DOI： 10.1097/00005792-200109000-00007

Source DB:  PubMed          Journal:  Medicine (Baltimore)        ISSN： 0025-7974            Impact factor:   1.889


× No keyword cloud information.
  22 in total

1.  Evaluation of safety and pharmacokinetics of sodium 2,2 dimethylbutyrate, a novel short chain fatty acid derivative, in a phase 1, double-blind, placebo-controlled, single-dose, and repeat-dose studies in healthy volunteers.

Authors:  Susan P Perrine; William A Wargin; Michael S Boosalis; Wayne J Wallis; Sally Case; Jeffrey R Keefer; Douglas V Faller; William C Welch; Ronald J Berenson
Journal:  J Clin Pharmacol       Date:  2011-03-21       Impact factor: 3.126

2.  Metformin induces FOXO3-dependent fetal hemoglobin production in human primary erythroid cells.

Authors:  Yankai Zhang; Alireza Paikari; Pavel Sumazin; Carly C Ginter Summarell; Jacy R Crosby; Eric Boerwinkle; Mitchell J Weiss; Vivien A Sheehan
Journal:  Blood       Date:  2018-06-08       Impact factor: 22.113

3.  Fetal globin induction--can it cure beta thalassemia?

Authors:  Susan P Perrine
Journal:  Hematology Am Soc Hematol Educ Program       Date:  2005

4.  Enhancement of growth and survival and alterations in Bcl-family proteins in beta-thalassemic erythroid progenitors by novel short-chain fatty acid derivatives.

Authors:  Serguei Castaneda; Michael S Boosalis; David Emery; Allison Thies; Douglas V Faller; Susan P Perrine
Journal:  Blood Cells Mol Dis       Date:  2005 Sep-Oct       Impact factor: 3.039

5.  Novel therapeutic candidates, identified by molecular modeling, induce γ-globin gene expression in vivo.

Authors:  Michael S Boosalis; Serguei A Castaneda; Marie Trudel; Rodwell Mabaera; Gary L White; Christopher H Lowrey; David W Emery; Marthe-Sandrine Eiymo Mwa Mpollo; Ling Shen; William A Wargin; Regine Bohacek; Douglas V Faller; Susan P Perrine
Journal:  Blood Cells Mol Dis       Date:  2011-08-15       Impact factor: 3.039

6.  Identification of novel small-molecule inducers of fetal hemoglobin using pharmacophore and 'PSEUDO' receptor models.

Authors:  Regine Bohacek; Michael S Boosalis; Colin McMartin; Douglas V Faller; Susan P Perrine
Journal:  Chem Biol Drug Des       Date:  2006-05       Impact factor: 2.817

7.  Induction of fetal globin in beta-thalassemia: Cellular obstacles and molecular progress.

Authors:  Susan P Perrine; Serguei A Castaneda; Michael S Boosalis; Gary L White; Brandon M Jones; Regine Bohacek
Journal:  Ann N Y Acad Sci       Date:  2005       Impact factor: 5.691

8.  A randomized phase I/II trial of HQK-1001, an oral fetal globin gene inducer, in β-thalassaemia intermedia and HbE/β-thalassaemia.

Authors:  Suthat Fucharoen; Adlette Inati; Noppadol Siritanaratku; Swee L Thein; William C Wargin; Suzanne Koussa; Ali Taher; Nattawara Chaneim; Michael Boosalis; Ronald Berenson; Susan P Perrine
Journal:  Br J Haematol       Date:  2013-03-27       Impact factor: 6.998

9.  Liquid chromatography-mass spectrometric assay for quantitation of the short-chain fatty acid, 2,2-dimethylbutyrate (NSC 741804), in rat plasma.

Authors:  Robert A Parise; Jan H Beumer; Cyrous O Kangani; Julianne L Holleran; Julie L Eiseman; Nicola F Smith; Joseph M Covey; Susan P Perrine; Merrill J Egorin
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2007-12-08       Impact factor: 3.205

10.  A phase 1/2 trial of HQK-1001, an oral fetal globin inducer, in sickle cell disease.

Authors:  Abdullah Kutlar; Kenneth Ataga; Marvin Reid; Elliott P Vichinsky; Lynne Neumayr; Loray Blair-Britt; Richard Labotka; Jonathan Glass; Jeffrey R Keefer; William A Wargin; Ronald Berenson; Susan P Perrine
Journal:  Am J Hematol       Date:  2012-08-07       Impact factor: 10.047
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.