Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Objective assessment of progression in Huntington's disease: a 3-year follow-up study.

Literature DB >> 11552034

Objective assessment of progression in Huntington's disease: a 3-year follow-up study.

R Reilmann¹, F Kirsten, L Quinn, H Henningsen, K Marder, A M Gordon.

Abstract

Objective measures to assess progression of Huntington's disease (HD) are desirable. The authors have previously found that patients with HD with higher Unified Huntington's Disease Rating Scale (UHDRS) motor scores exhibited higher variability of isometric grip forces while grasping an object. Therefore, the authors assessed grip force variability during this task in 10 HD patients with a 3-year follow-up. Grip force variability increased in all patients at the follow-up. Thus, grip force variability during grasping might be an objective and quantitative measure to assess motor deficits associated with the progression of HD.

Entities: Disease Gene Species

Mesh：

Year: 2001 PMID： 11552034 DOI： 10.1212/wnl.57.5.920

Source DB: PubMed Journal: Neurology ISSN： 0028-3878 Impact factor: 9.910

Keyword Cloud
Cited

22 in total

Review 1. Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features.

Authors: Ina Han; YiMei You; Jeffrey H Kordower; Scott T Brady; Gerardo A Morfini
Journal: J Neurochem Date: 2010-03-17 Impact factor: 5.372

Review 2. Basal ganglia mechanisms underlying precision grip force control.

Authors: Janey Prodoehl; Daniel M Corcos; David E Vaillancourt
Journal: Neurosci Biobehav Rev Date: 2009-03-14 Impact factor: 8.989

3. Application of Quantitative Motor Assessments in Friedreich Ataxia and Evaluation of Their Relation to Clinical Measures.

Authors: Christian Hohenfeld; Imis Dogan; Robin Schubert; Claire Didszun; Ludger Schöls; Matthis Synofzik; Ilaria A Giordano; Thomas Klockgether; Jörg B Schulz; Ralf Reilmann; Kathrin Reetz
Journal: Cerebellum Date: 2019-10 Impact factor: 3.847

Review 4. Huntington disease: natural history, biomarkers and prospects for therapeutics.

Authors: Christopher A Ross; Elizabeth H Aylward; Edward J Wild; Douglas R Langbehn; Jeffrey D Long; John H Warner; Rachael I Scahill; Blair R Leavitt; Julie C Stout; Jane S Paulsen; Ralf Reilmann; Paul G Unschuld; Alice Wexler; Russell L Margolis; Sarah J Tabrizi
Journal: Nat Rev Neurol Date: 2014-03-11 Impact factor: 42.937

5. Effects of focal hand dystonia on visually guided and internally guided force control.

Authors: J Prodoehl; D M Corcos; D E Vaillancourt
Journal: J Neurol Neurosurg Psychiatry Date: 2006-05-11 Impact factor: 10.154

6. Quantitative motor assessment of dyskinesias in Parkinson's disease.

Authors: Eva Schaeffer; Walter Maetzler; Inga Liepelt-Scarfone; Christian Sass; Ralf Reilmann; Daniela Berg
Journal: J Neural Transm (Vienna) Date: 2015-02-25 Impact factor: 3.575

7. Tapping linked to function and structure in premanifest and symptomatic Huntington disease.

Authors: N Bechtel; R I Scahill; H D Rosas; T Acharya; S J A van den Bogaard; C Jauffret; M J Say; A Sturrock; H Johnson; C E Onorato; D H Salat; A Durr; B R Leavitt; R A C Roos; G B Landwehrmeyer; D R Langbehn; J C Stout; S J Tabrizi; R Reilmann
Journal: Neurology Date: 2010-11-10 Impact factor: 9.910