Literature DB >> 11551468

Novel concepts for selection of catalytic activity.

P Soumillion1, J Fastrez.   

Abstract

The selection of mutant enzymes with novel properties from libraries is emerging as a very powerful strategy for enzyme engineering. The past year has witnessed significant progress on several fronts: new and improved methods have been developed for the creation of libraries and advances have been made in screening and selection techniques. The results achieved demonstrate the enormous potential of the methods and leave questions open for further studies.

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Year:  2001        PMID： 11551468     DOI： 10.1016/s0958-1669(00)00232-9

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN： 0958-1669            Impact factor:   9.740


  7 in total

1.  Nitrogen-regulated hypermutator strain of Synechococcus sp. for use in in vivo artificial evolution.

Authors:  Daniel Emlyn-Jones; G Dean Price; T John Andrews
Journal:  Appl Environ Microbiol       Date:  2003-11       Impact factor: 4.792

2.  Directed evolution of an extremely fast phosphotriesterase by in vitro compartmentalization.

Authors:  Andrew D Griffiths; Dan S Tawfik
Journal:  EMBO J       Date:  2003-01-02       Impact factor: 11.598

3.  Crystallization and preliminary X-ray diffraction analysis of kanamycin-binding β-lactamase in complex with its ligand.

Authors:  Karen Van de Water; Sameh H Soror; Alexandre Wohlkonig; Nico A J van Nuland; Alexander N Volkov
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2011-05-26

4.  Reactibodies generated by kinetic selection couple chemical reactivity with favorable protein dynamics.

Authors:  Ivan Smirnov; Eugénie Carletti; Inna Kurkova; Florian Nachon; Yvain Nicolet; Vladimir A Mitkevich; Hélène Débat; Bérangère Avalle; Alexey A Belogurov; Nikita Kuznetsov; Andrey Reshetnyak; Patrick Masson; Alexander G Tonevitsky; Natalia Ponomarenko; Alexander A Makarov; Alain Friboulet; Alfonso Tramontano; Alexander Gabibov
Journal:  Proc Natl Acad Sci U S A       Date:  2011-09-06       Impact factor: 11.205

5.  Selection of a human butyrylcholinesterase-like antibody single-chain variable fragment resistant to AChE inhibitors from a phage library expressed in E. coli.

Authors:  Adriano Podestà; Serena Rossi; Ilaria Massarelli; Sara Carpi; Barbara Adinolfi; Stefano Fogli; Anna Maria Bianucci; Paola Nieri
Journal:  MAbs       Date:  2014 Jul-Aug       Impact factor: 5.857

6.  Routes to covalent catalysis by reactive selection for nascent protein nucleophiles.

Authors:  Andrey V Reshetnyak; Maria Francesca Armentano; Natalia A Ponomarenko; Domenica Vizzuso; Oxana M Durova; Rustam Ziganshin; Marina Serebryakova; Vadim Govorun; Gennady Gololobov; Herbert C Morse; Alain Friboulet; Sudesh P Makker; Alexander G Gabibov; Alfonso Tramontano
Journal:  J Am Chem Soc       Date:  2007-11-29       Impact factor: 15.419

Review 7.  Tailor-made biocatalysts: combining thermodynamics, organic synthesis, molecular biology, biochemistry and microbiology for the design of enzyme selections.

Authors:  Jean-Luc Jestin
Journal:  Comput Struct Biotechnol J       Date:  2012-10-28       Impact factor: 7.271
  7 in total

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