Literature DB >> 11551201

Mammaglobin is found in breast tissue as a complex with BU101.

T L Colpitts1, P Billing-Medel, P Friedman, E N Granados, M Hayden, S Hodges, N Menhart, L Roberts, J Russell, S D Stroupe.   

Abstract

The mammaglobin gene has been shown to be preferentially expressed in breast tissue. Few genes match its specificity. Mammaglobin has generated much interest, and studies are ongoing to develop diagnostic tests for breast cancer based on the detection of mammaglobin. While searching the Incyte Genomics Lifeseq database for tissue-specific markers, we observed a second secretoglobin, BU101, also known as lipophilin B. We report here that mammaglobin, in breast tissue, is found as a complex with BU101. The complex was isolated from breast cancer tissue and was characterized as the biologically relevant form of mammaglobin.

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Year:  2001        PMID： 11551201     DOI： 10.1021/bi010284f

Source DB:  PubMed          Journal:  Biochemistry        ISSN： 0006-2960            Impact factor:   3.162


  9 in total

1.  Detection of circulating tumor cells in peripheral blood of breast cancer patients during or after therapy using a multigene real-time RT-PCR assay.

Authors:  Barbara K Zehentner; Heather Secrist; Dawn C Hayes; Xinqun Zhang; Richard C Ostenson; Steven Loop; Gary Goodman; Raymond L Houghton; David H Persing
Journal:  Mol Diagn Ther       Date:  2006       Impact factor: 4.074

2.  Relationship between mammaglobin expression and estrogen receptor status in breast tumors.

Authors:  Xiao-feng Guan; Mohammad K Hamedani; Adewale Adeyinka; Christina Walker; Angela Kemp; Leigh C Murphy; Peter H Watson; Etienne Leygue
Journal:  Endocrine       Date:  2003-08       Impact factor: 3.633

3.  Expression analysis of mammaglobin A (SCGB2A2) and lipophilin B (SCGB1D2) in more than 300 human tumors and matching normal tissues reveals their co-expression in gynecologic malignancies.

Authors:  Menelaos Zafrakas; Beate Petschke; Andreas Donner; Florian Fritzsche; Glen Kristiansen; Ruth Knüchel; Edgar Dahl
Journal:  BMC Cancer       Date:  2006-04-09       Impact factor: 4.430

Review 4.  Human mammaglobin in breast cancer: a brief review of its clinical utility.

Authors:  Fawwaz Shakir Al Joudi
Journal:  Indian J Med Res       Date:  2014-05       Impact factor: 2.375

5.  Mammaglobin as a potential molecular target for breast cancer drug delivery.

Authors:  Lian Zuo; Ly Li; Qian Wang; Timothy P Fleming; Shaojin You
Journal:  Cancer Cell Int       Date:  2009-03-23       Impact factor: 5.722

6.  Elevated mammaglobin (h-MAM) expression in breast cancer is associated with clinical and biological features defining a less aggressive tumour phenotype.

Authors:  M J Núñez-Villar; F Martínez-Arribas; M Pollán; A R Lucas; J Sánchez; A Tejerina; J Schneider
Journal:  Breast Cancer Res       Date:  2003-03-06       Impact factor: 6.466

7.  Secretoglobin expression in ovarian carcinoma: lipophilin B gene upregulation as an independent marker of better prognosis.

Authors:  Eliana Bignotti; Renata A Tassi; Stefano Calza; Antonella Ravaggi; Elisa Rossi; Carla Donzelli; Paola Todeschini; Chiara Romani; Elisabetta Bandiera; Laura Zanotti; Mario Carnazza; Francesco Quadraro; Germana Tognon; Enrico Sartori; Sergio Pecorelli; Dana M Roque; Alessandro D Santin
Journal:  J Transl Med       Date:  2013-07-02       Impact factor: 5.531

8.  In vitro selections of mammaglobin A and mammaglobin B aptamers for the recognition of circulating breast tumor cells.

Authors:  Eman M Hassan; William G Willmore; Bruce C McKay; Maria C DeRosa
Journal:  Sci Rep       Date:  2017-11-03       Impact factor: 4.379

9.  Over-expression of mammaglobin-B in canine mammary tumors.

Authors:  Mamta Pandey; B V Sunil Kumar; Kuldip Gupta; Ram Saran Sethi; Ashwani Kumar; Ramneek Verma
Journal:  BMC Vet Res       Date:  2018-06-15       Impact factor: 2.741
  9 in total

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