Literature DB >> 1155108

Influence of therapeutic concentrations of phenylbutazone on granulocyte function.

C O Solberg.   

Abstract

The influence of therapeutic concentrations of phenylbutazone on human granulocyte function has been examined using a method which facilitates a precise in vitro evaluation of the phagocytic and bactericidal activities of polymorphonuclear leucocytes. Phenylbutazone caused a marked reduction in intracellular killing of bacteria by the granulocytes. Whether this inhibition of granulocyte function also takes place in vivo resulting in enhanced susceptibility to infection, remains unknown.

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Year:  1975        PMID： 1155108     DOI： 10.1111/j.1699-0463.1975.tb00077.x

Source DB:  PubMed          Journal:  Acta Pathol Microbiol Scand B        ISSN： 0105-0656


  7 in total

1.  Altered antigen-presentation in the induction of the in-vitro antigen-specific T helper cell function in patients with chronic granulomatous disease.

Authors:  C J Heijnen; J W van der Meer; B J Zegers
Journal:  Clin Exp Immunol       Date:  1986-10       Impact factor: 4.330

2.  Participation of immunoglobulins and complement components in the intracellular killing of Staphylococcus aureus and Escherichia coli by human granulocytes.

Authors:  P C Leijh; M T van den Barselaar; M R Daha; R van Furth
Journal:  Infect Immun       Date:  1981-09       Impact factor: 3.441

3.  Regulation of human monocyte/macrophage function by extracellular matrix. Adherence of monocytes to collagen matrices enhances phagocytosis of opsonized bacteria by activation of complement receptors and enhancement of Fc receptor function.

Authors:  S L Newman; M A Tucci
Journal:  J Clin Invest       Date:  1990-09       Impact factor: 14.808

4.  Requirement of extracellular complement and immunoglobulin for intracellular killing of micro-organisms by human monocytes.

Authors:  P C Leijh; M T van den Barselaar; T L van Zwet; M R Daha; R van Furth
Journal:  J Clin Invest       Date:  1979-04       Impact factor: 14.808

5.  Kinetics of phagocytosis and intracellular killing of Candida albicans by human granulocytes and monocytes.

Authors:  P C Leijh; M T van den Barselaar; R van Furth
Journal:  Infect Immun       Date:  1977-08       Impact factor: 3.441

6.  Effect of extracellular serum in the stimulation of intracellular killing of streptococci by human monocytes.

Authors:  P C Leijh; T L van Zwet; R van Furth
Journal:  Infect Immun       Date:  1980-11       Impact factor: 3.441

7.  Nonsteroidal Anti-Inflammatory Drug without Antibiotics for Acute Viral Infection Increases the Empyema Risk in Children: A Matched Case-Control Study.

Authors:  Muriel Le Bourgeois; Agnès Ferroni; Marianne Leruez-Ville; Emmanuelle Varon; Caroline Thumerelle; François Brémont; Michael J Fayon; Christophe Delacourt; Caroline Ligier; Laurence Watier; Didier Guillemot
Journal:  J Pediatr       Date:  2016-06-20       Impact factor: 4.406
  7 in total

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