OBJECTIVE: To evaluate the relative impact of sex, type of onset, course of disease, age at onset, duration of disease and status of HLA-B27, antinuclear antibodies (ANA), and rheumatoid factor on the risk of developing a condylar erosion. METHODS: Condylar changes of the temporomandibular joint (TMJ) were diagnosed on orthopantomograms from 169 consecutive patients with juvenile chronic arthritis (JCA). A multiple regression analysis was applied to establish the relative weight of the independent variables affecting the severity of the condylar erosion. RESULTS: It was found that 62.1% of the patients exhibited condylar resorption. The highest prevalence was seen in children with a polyarticular onset or course of disease and early age at onset and severe resorption was also frequent in these groups. Patients with positive ANA also had a high prevalence but with a mild degree of resorption. In contrast, HLA-B27 positive patients had a lower risk of TMJ involvement and resorptive changes of the condyle. CONCLUSION: Polyarticular and early onset arthritis are associated with a high risk for TMJ involvement and a severe condylar bone loss can be expected. ANA positive patients have a high prevalence, and B27 positive patients have a low prevalence of TMJ arthritis but in both subgroups, the outcome of the bone resorptive process is mild.
OBJECTIVE: To evaluate the relative impact of sex, type of onset, course of disease, age at onset, duration of disease and status of HLA-B27, antinuclear antibodies (ANA), and rheumatoid factor on the risk of developing a condylar erosion. METHODS: Condylar changes of the temporomandibular joint (TMJ) were diagnosed on orthopantomograms from 169 consecutive patients with juvenile chronic arthritis (JCA). A multiple regression analysis was applied to establish the relative weight of the independent variables affecting the severity of the condylar erosion. RESULTS: It was found that 62.1% of the patients exhibited condylar resorption. The highest prevalence was seen in children with a polyarticular onset or course of disease and early age at onset and severe resorption was also frequent in these groups. Patients with positive ANA also had a high prevalence but with a mild degree of resorption. In contrast, HLA-B27 positive patients had a lower risk of TMJ involvement and resorptive changes of the condyle. CONCLUSION: Polyarticular and early onset arthritis are associated with a high risk for TMJ involvement and a severe condylar bone loss can be expected. ANA positive patients have a high prevalence, and B27 positive patients have a low prevalence of TMJ arthritis but in both subgroups, the outcome of the bone resorptive process is mild.
Authors: Liete M L Figueiredo Zwir; Maria Teresa R A Terreri; Soraia Ale Sousa; Artur Rocha Corrêa Fernandes; Antônio Sérgio Guimarães; Maria Odete E Hilário Journal: Clin Rheumatol Date: 2015-04-07 Impact factor: 2.980
Authors: Ola A Abdul-Aziez; Nayera Z Saber; Samah A El-Bakry; Ahmed A Mohammad; Sahar S Abdel-Maksud; Yaser Ali Journal: Pak J Biol Sci Date: 2010-02-01
Authors: Camila Pugliese; Roberta T A van der Vinne; Lucia M A Campos; Priscila R Guardieiro; Cynthia Saviolli; Eloisa Bonfá; Rosa M R Pereira; Vilma S Viana; Eduardo F Borba; Clovis A Silva Journal: Clin Rheumatol Date: 2015-12-01 Impact factor: 2.980
Authors: Dimitri A Parra; Melissa Chan; Ganesh Krishnamurthy; Lynn Spiegel; Joao G Amaral; Michael J Temple; Philip R John; Bairbre L Connolly Journal: Pediatr Radiol Date: 2010-03-04
Authors: Elka Miller; Emilio J Inarejos Clemente; Nikolay Tzaribachev; Saurabh Guleria; Mirkamal Tolend; Arthur B Meyers; Thekla von Kalle; Jennifer Stimec; Bernd Koos; Simone Appenzeller; Linda Z Arvidsson; Eva Kirkhus; Andrea S Doria; Christian J Kellenberger; Tore A Larheim Journal: Pediatr Radiol Date: 2018-05-08