Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Incorporation of positively charged deoxynucleic S-methylthiourea linkages into oligodeoxyribonucleotides.

Literature DB >> 11549438

Incorporation of positively charged deoxynucleic S-methylthiourea linkages into oligodeoxyribonucleotides.

Abstract

Oligodeoxyribonucleic acids (15- and 18-mers) containing both negatively charged phosphate and positively charged S-methyl thiourea internucleoside linkages (DNmt/DNA chimera) have been synthesized. DNA binding characteristics and nuclease resistance of DNmt/DNA chimera have been evaluated.

Entities: Chemical Species

Mesh：

Substances：

Year: 2001 PMID： 11549438 DOI： 10.1016/s0960-894x(01)00455-3

Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823

Keyword Cloud
Cited

6 in total

1. (Pseudo)amide-linked oligosaccharide mimetics: molecular recognition and supramolecular properties.

Authors: José L Jiménez Blanco; Fernando Ortega-Caballero; Carmen Ortiz Mellet; José M García Fernández
Journal: Beilstein J Org Chem Date: 2010-02-22 Impact factor: 2.883

2. NAA-modified DNA oligonucleotides with zwitterionic backbones: stereoselective synthesis of A-T phosphoramidite building blocks.

Authors: Boris Schmidtgall; Claudia Höbartner; Christian Ducho
Journal: Beilstein J Org Chem Date: 2015-01-13 Impact factor: 2.883

3. Oligonucleotides with Cationic Backbone and Their Hybridization with DNA: Interplay of Base Pairing and Electrostatic Attraction.

Authors: Boris Schmidtgall; Arne Kuepper; Melissa Meng; Tom N Grossmann; Christian Ducho
Journal: Chemistry Date: 2017-12-27 Impact factor: 5.236

Incorporation of positively charged deoxynucleic S-methylthiourea linkages into oligodeoxyribonucleotides.

1. (Pseudo)amide-linked oligosaccharide mimetics: molecular recognition and supramolecular properties.

2. NAA-modified DNA oligonucleotides with zwitterionic backbones: stereoselective synthesis of A-T phosphoramidite building blocks.

3. Oligonucleotides with Cationic Backbone and Their Hybridization with DNA: Interplay of Base Pairing and Electrostatic Attraction.

4. Enhanced Stability of DNA Oligonucleotides with Partially Zwitterionic Backbone Structures in Biological Media.

Review 5. Oligonucleotide analogues with cationic backbone linkages.

6. Towards Zwitterionic Oligonucleotides with Improved Properties: the NAA/LNA-Gapmer Approach.