Literature DB >> 11546569

Spinal leptomeningeal metastasis from cerebral glioblastoma multiforme presenting with radicular pain: case report and literature review.

S Alatakis1, G M Malham, C Thien.   

Abstract

BACKGROUND: We present a case of spinal leptomeningeal metastasis from an intracranial glioblastoma multiforme that presented with radicular pain. CASE DESCRIPTION: A 55-year-old man with a previously treated supratentorial glioblastoma multiforme presented with a 12-month history of thoracic radicular pain. MRI of the thoracic spine demonstrated an intradural extramedullary metastatic tumor deposit at the levels of T8-T10. External beam radiotherapy to the thoracic spine provided a minimal decrease in the intensity of the radicular pain. The lack of appreciation of the metastatic potential of the primary intracranial tumor resulted in delayed diagnosis and treatment.
CONCLUSION: Spinal leptomeningeal metastasis needs to be suspected in patients with a past history of intracranial glioblastoma multiforme, who present with the clinical features of radiculopathy or myelopathy. Awareness of this condition will facilitate appropriate intervention.

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Year:  2001        PMID: 11546569     DOI: 10.1016/s0090-3019(01)00459-1

Source DB:  PubMed          Journal:  Surg Neurol        ISSN: 0090-3019


  22 in total

1.  The clinical features of spinal leptomeningeal dissemination from malignant gliomas.

Authors:  Jung-Sik Bae; Seung-Ho Yang; Woan-Soo Yoon; Seok-Gu Kang; Yong-Kil Hong; Sin-Soo Jeun
Journal:  J Korean Neurosurg Soc       Date:  2011-06-30

2.  Spinal cord metastasis in a patient treated with bevacizumab for glioblastoma.

Authors:  Anna J Lomax; Costas K Yannakou; Mark A Rosenthal
Journal:  Target Oncol       Date:  2013-02-21       Impact factor: 4.493

3.  Freiburg neuropathology case conference: widespread mass lesions after resection of a glioblastoma multiforme.

Authors:  C A Taschner; S Brendecke; A Weyerbrock; K Egger; M Prinz
Journal:  Clin Neuroradiol       Date:  2012-11-07       Impact factor: 3.649

4.  Unusual massive spinal metastases from a recurrent intracranial glioblastoma multiforme.

Authors:  Mehmet Basmaci; Askin Esen Hasturk; Erdal Resit Yilmaz; Hayri Kertmen; Bora Gurer
Journal:  Indian J Surg Oncol       Date:  2013-04-02

Review 5.  Bone marrow metastases from glioblastoma multiforme--A case report and review of the literature.

Authors:  Vandana Rajagopalan; Francois G El Kamar; Rose Thayaparan; Michael L Grossbard
Journal:  J Neurooncol       Date:  2005-04       Impact factor: 4.130

Review 6.  Leptomeningeal Spread in Glioblastoma: Diagnostic and Therapeutic Challenges.

Authors:  Cristina Birzu; Suzanne Tran; Franck Bielle; Mehdi Touat; Karima Mokhtari; Nadia Younan; Dimitri Psimaras; Khe Hoang-Xuan; Marc Sanson; Jean-Yves Delattre; Ahmed Idbaih
Journal:  Oncologist       Date:  2020-08-31

7.  Is surgical spinal decompression for supratentorial GBM symptomatic drop down metastasis warranted? A case report and review of literature.

Authors:  Muhammad Babar Khan; Muhammad Riaz; Muhammad Ehsan Bari
Journal:  Surg Neurol Int       Date:  2014-03-27

8.  Malignant spinal cord compression in cerebral glioblastoma multiforme: a multicenter case series and review of the literature.

Authors:  Alexander Tinchon; Stefan Oberndorfer; Christine Marosi; Roberta Rudà; Cornelia Sax; Bernadette Calabek; Wolfgang Grisold
Journal:  J Neurooncol       Date:  2012-08-14       Impact factor: 4.130

9.  A comparative study of primary and recurrent human glioblastoma multiforme using the small animal imaging and molecular expressive profiles.

Authors:  Liang-Ting Lin; Shih-Hwa Chiou; Te-Wei Lee; Ren-Shyan Liu; Jeng-Jong Hwang; Chih-Hsien Chang; Hsin-I Ma; Yi-Jang Lee
Journal:  Mol Imaging Biol       Date:  2013-06       Impact factor: 3.488

10.  Incidence of initial spinal metastasis in glioblastoma patients and the importance of spinal screening using MRI.

Authors:  Ichiyo Shibahara; Ryuta Saito; Yoshinari Osada; Masayuki Kanamori; Yukihiko Sonoda; Toshihiro Kumabe; Shunji Mugikura; Mika Watanabe; Teiji Tominaga
Journal:  J Neurooncol       Date:  2018-11-09       Impact factor: 4.130

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