Literature DB >> 11545493

A 212Pb generator based on a 228Th source.

S Hassfjell1.   

Abstract

A two-compartment 212Pb generator has been constructed and characterized physically and chemically. It is based on transport by airflow of gaseous 220Rn emanating from thin layers of [228Th]barium stearate. 220Rn is collected in a glass bubbler by extraction into an organic solvent and solidified at temperatures below -72 degrees C. Tracer studies show that the decay product 212Pb can be recovered with approximately 70% yield. It is suggested that this generator design could accommodate therapeutic levels of 212Pb/228Th.

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Year:  2001        PMID： 11545493     DOI： 10.1016/s0969-8043(00)00372-9

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN： 0969-8043            Impact factor:   1.513


  9 in total

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2.  Towards translation of 212Pb as a clinical therapeutic; getting the lead in!

Authors:  Kwon Yong; Martin W Brechbiel
Journal:  Dalton Trans       Date:  2011-03-04       Impact factor: 4.390

Review 3.  Applications of heteronuclear NMR spectroscopy in biological and medicinal inorganic chemistry.

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5.  Production and Supply of α-Particle-Emitting Radionuclides for Targeted α-Therapy.

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Journal:  J Nucl Med       Date:  2021-07-22       Impact factor: 11.082

6.  In situ Generated <sup>212</sup>Pb-PSMA Ligand in a <sup>224</sup>Ra-Solution for Dual Targeting of Prostate Cancer Sclerotic Stroma and PSMA-positive Cells.

Authors:  Vilde Y Stenberg; Asta Juzeniene; Øyvind S Bruland; Roy H Larsen
Journal:  Curr Radiopharm       Date:  2020

7.  Production, purification, and radiolabeling of the 203Pb/212Pb theranostic pair.

Authors:  Brooke L McNeil; Andrew K H Robertson; Winnie Fu; Hua Yang; Cornelia Hoehr; Caterina F Ramogida; Paul Schaffer
Journal:  EJNMMI Radiopharm Chem       Date:  2021-02-01

8.  Radon-220 diffusion from 224Ra-labeled calcium carbonate microparticles: Some implications for radiotherapeutic use.

Authors:  Elisa Napoli; Tina B Bønsdorff; Ida Sofie Jorstad; Øyvind S Bruland; Roy H Larsen; Sara Westrøm
Journal:  PLoS One       Date:  2021-03-04       Impact factor: 3.240

Review 9.  212Pb: Production Approaches and Targeted Therapy Applications.

Authors:  Konstantin V Kokov; Bayirta V Egorova; Marina N German; Ilya D Klabukov; Michael E Krasheninnikov; Antonius A Larkin-Kondrov; Kseniya A Makoveeva; Michael V Ovchinnikov; Maria V Sidorova; Dmitry Y Chuvilin
Journal:  Pharmaceutics       Date:  2022-01-13       Impact factor: 6.321
  9 in total

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