| Literature DB >> 11544030 |
P Z Anastasiadis1, A B Reynolds.
Abstract
Three recent reports indicate that p120-catenin can modulate the activities of RhoA, Rac and Cdc42, suggesting an elegant and previously unexpected mechanism for regulating the balance between adhesive and motile cellular phenotypes. The observations in these reports provide important new clues toward p120's mechanism of action and provide a potential explanation for the metastatic phenotype exhibited in carcinoma cells that have lost E cadherin expression.Entities:
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Year: 2001 PMID： 11544030 DOI： 10.1016/s0955-0674(00)00258-1
Source DB: PubMed Journal: Curr Opin Cell Biol ISSN： 0955-0674 Impact factor: 8.382