| Literature DB >> 11544025 |
Abstract
Transendothelial migration of leukocytes involves the spatiotemporal regulation of adhesion molecules, chemokines and cytoskeletal regulators. Recent results show that distinct steps of leukocyte transendothelial migration are regulated by sequential integrin activation and coordinated Rho family GTPase activity. Progress has been made in understanding how the dynamic regulation of these molecules translates into leukocyte transmigration.Mesh:
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Year: 2001 PMID: 11544025 DOI: 10.1016/s0955-0674(00)00253-2
Source DB: PubMed Journal: Curr Opin Cell Biol ISSN: 0955-0674 Impact factor: 8.382