Literature DB >> 11544002

The role of cytotoxicity in lymphocyte homeostasis.

G de Saint Basile1, A Fischer.   

Abstract

Several human inherited immune disorders lead to the same fatal lymphoproliferative syndrome, called the hemophagocytic syndrome. Through defective perforin expression or transport, these disorders highlight the determinant role of the secretory cytotoxic pathway in the regulation of the immune response and in lymphocyte homeostasis. In addition, new effectors of this secretory pathway have been identified.

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Year:  2001        PMID： 11544002     DOI： 10.1016/s0952-7915(00)00257-0

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  18 in total

1.  Griscelli syndrome types 1 and 2.

Authors:  Gaël Ménasché; Alain Fischer; Geneviève de Saint Basile
Journal:  Am J Hum Genet       Date:  2002-11       Impact factor: 11.025

2.  Granzymes and caspase 3 play important roles in control of gammaherpesvirus latency.

Authors:  Joy Loh; Dori A Thomas; Paula A Revell; Timothy J Ley; Herbert W Virgin
Journal:  J Virol       Date:  2004-11       Impact factor: 5.103

Review 3.  Therapeutic potential of CD8+ cytotoxic T lymphocytes in SLE.

Authors:  I Puliaeva; R Puliaev; C S Via
Journal:  Autoimmun Rev       Date:  2008-08-24       Impact factor: 9.754

4.  Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells.

Authors:  Marjorie Côte; Mickaël M Ménager; Agathe Burgess; Nizar Mahlaoui; Capucine Picard; Catherine Schaffner; Fahad Al-Manjomi; Musa Al-Harbi; Abdullah Alangari; Françoise Le Deist; Andrew R Gennery; Nathalie Prince; Astrid Cariou; Patrick Nitschke; Ulrich Blank; Gehad El-Ghazali; Gaël Ménasché; Sylvain Latour; Alain Fischer; Geneviève de Saint Basile
Journal:  J Clin Invest       Date:  2009-11-02       Impact factor: 14.808

5.  Contribution of NK cells to the innate phase of host protection against an intracellular bacterium targeting systemic endothelium.

Authors:  Rong Fang; Nahed Ismail; David H Walker
Journal:  Am J Pathol       Date:  2012-05-19       Impact factor: 4.307

Review 6.  Mycobacterium tuberculosis-specific CD8+ T cells and their role in immunity.

Authors:  Joshua S M Woodworth; Samuel M Behar
Journal:  Crit Rev Immunol       Date:  2006       Impact factor: 2.214

7.  Pre- and post-natal treatment of hemophagocytic lymphohistiocytosis.

Authors:  Ami J Shah; Neena Kapoor; Robert M Cooper; Gay M Crooks; Carl Lenarsky; Hisham Abdel-Azim; Shi Qi Wu; Kathy Wilson; Kenneth I Weinberg; Robertson Parkman; Donald B Kohn
Journal:  Pediatr Blood Cancer       Date:  2009-01       Impact factor: 3.167

8.  In vivo maturation of allo-specific CD8 CTL and prevention of lupus-like graft-versus-host disease is critically dependent on T cell signaling through the TNF p75 receptor but not the TNF p55 receptor.

Authors:  Kateryna Soloviova; Maksym Puliaiev; Mark Haas; Charles S Via
Journal:  J Immunol       Date:  2013-03-22       Impact factor: 5.422

9.  Pediatric hemophagocytic syndromes: a diagnostic and therapeutic challenge.

Authors:  Nada Jabado; Christine McCusker; Genevieve de Saint Basile
Journal:  Allergy Asthma Clin Immunol       Date:  2005-12-15       Impact factor: 3.406

10.  Griscelli syndrome restricted to hypopigmentation results from a melanophilin defect (GS3) or a MYO5A F-exon deletion (GS1).

Authors:  Gaël Ménasché; Chen Hsuan Ho; Ozden Sanal; Jérôme Feldmann; Ilhan Tezcan; Fügen Ersoy; Anne Houdusse; Alain Fischer; Geneviève de Saint Basile
Journal:  J Clin Invest       Date:  2003-08       Impact factor: 14.808
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