Literature DB >> 11543968

A novel cytotoxic flavonoid glycoside from Physalis angulata.

N Ismail1, M Alam.   

Abstract

A new flavonol glycoside, myricetin 3-O-neohesperidoside (1) was isolated from a cytotoxic MeOH extract of the leaves of Physalis angulata. Compound 1 showed remarkable cytotoxicity in vitro against murine leukemia cell line P-388, epidermoid carcinoma of the nasopharynx KB-16 cells, and lung adenocarcinoma A-549 with ED(50) values of 0.048, 0.50 and 0.55 microg ml(-1), respectively.

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Year:  2001        PMID： 11543968     DOI： 10.1016/s0367-326x(01)00281-7

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  7 in total

1.  Transcriptome-wide identification of microRNAs and functional insights inferred from microRNA-target pairs in Physalis angulata L.

Authors:  Jiangjie Lu; Min Xu; Jiahui Cai; Dongliang Yu; Yijun Meng; Huizhong Wang
Journal:  Plant Signal Behav       Date:  2019-06-11

2.  Antiproliferative activity of vitexin-2-O-xyloside and avenanthramides on CaCo-2 and HepG2 cancer cells occurs through apoptosis induction and reduction of pro-survival mechanisms.

Authors:  Emanuele Salvatore Scarpa; Elena Antonini; Francesco Palma; Michele Mari; Paolino Ninfali
Journal:  Eur J Nutr       Date:  2017-03-10       Impact factor: 5.614

3.  Biochemical crypsis in the avoidance of natural enemies by an insect herbivore.

Authors:  Consuelo M De Moraes; Mark C Mescher
Journal:  Proc Natl Acad Sci U S A       Date:  2004-06-07       Impact factor: 11.205

4.  Physalin F induces cell apoptosis in human renal carcinoma cells by targeting NF-kappaB and generating reactive oxygen species.

Authors:  Szu-Ying Wu; Yann-Lii Leu; Ya-Ling Chang; Tian-Shung Wu; Ping-Chung Kuo; Yu-Ren Liao; Che-Ming Teng; Shiow-Lin Pan
Journal:  PLoS One       Date:  2012-07-16       Impact factor: 3.240

5.  Sagan Dalya Tea, a New "Old" Probable Adaptogenic Drug: Metabolic Characterization and Bioactivity Potentials of Rhododendron adamsii Leaves.

Authors:  Daniil N Olennikov; Vyacheslav M Nikolaev; Nadezhda K Chirikova
Journal:  Antioxidants (Basel)       Date:  2021-05-27

6.  Physalis angulata induces in vitro differentiation of murine bone marrow cells into macrophages.

Authors:  Bruno José Martins da Silva; Ana Paula D Rodrigues; Luis Henrique S Farias; Amanda Anastácia P Hage; Jose Luiz M Do Nascimento; Edilene O Silva
Journal:  BMC Cell Biol       Date:  2014-10-03       Impact factor: 4.241

7.  Phenolic constituents and antioxidant properties of five wild species of Physalis (Solanaceae).

Authors:  José Roberto Medina-Medrano; Norma Almaraz-Abarca; M Socorro González-Elizondo; José Natividad Uribe-Soto; Laura Silvia González-Valdez; Yolanda Herrera-Arrieta
Journal:  Bot Stud       Date:  2015-09-18       Impact factor: 2.787
  7 in total

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