Literature DB >> 11537332

Fertilization of frog eggs on a Sounding Rocket in space.

G A Ubbels1, W Berendsen, J Narraway.   

Abstract

During the TEXUS-17 flight (April/May 1988) eggs of a higher organism, the anuran amphibian Xenopus laevis, have for the first time been successfully fertilized under microgravity on a Sounding Rocket. This result also implies that Life Sciences Experiments of Short Duration can be carried out on Sounding Rockets. The latter can therefore function as additional carriers for such experiments. Histological sections of the experimental material demonstrated the penetration of sperm into eggs, while SEM analysis revealed the differentiation of characteristic egg surface structures. Our TEXUS-17 experiment convincingly shows that the modified automatic experiment container, originally designed for experimental BR 52NL on the D1-mission, now functions flawlessly. Eight containers were flown in an airtight, well-isolated box (TEM 06-15), and a similar set was activated on Earth, two hours later. The analysis of the biological material is in progress.

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Year:  1989        PMID: 11537332     DOI: 10.1016/0273-1177(89)90073-2

Source DB:  PubMed          Journal:  Adv Space Res        ISSN: 0273-1177            Impact factor:   2.152


  7 in total

1.  Healthy offspring from freeze-dried mouse spermatozoa held on the International Space Station for 9 months.

Authors:  Sayaka Wakayama; Yuko Kamada; Kaori Yamanaka; Takashi Kohda; Hiromi Suzuki; Toru Shimazu; Motoki N Tada; Ikuko Osada; Aiko Nagamatsu; Satoshi Kamimura; Hiroaki Nagatomo; Eiji Mizutani; Fumitoshi Ishino; Sachiko Yano; Teruhiko Wakayama
Journal:  Proc Natl Acad Sci U S A       Date:  2017-05-22       Impact factor: 11.205

2.  A major effect of simulated microgravity on several stages of preimplantation mouse development is lethality associated with elevated phosphorylated SAPK/JNK.

Authors:  Yingchun Wang; Yufen Xie; Dana Wygle; Hayley H Shen; Elizabeth E Puscheck; Daniel A Rappolee
Journal:  Reprod Sci       Date:  2009-06-22       Impact factor: 3.060

3.  Male mice, caged in the International Space Station for 35 days, sire healthy offspring.

Authors:  Takafumi Matsumura; Taichi Noda; Masafumi Muratani; Risa Okada; Mutsumi Yamane; Ayako Isotani; Takashi Kudo; Satoru Takahashi; Masahito Ikawa
Journal:  Sci Rep       Date:  2019-09-24       Impact factor: 4.379

Review 4.  Effects of Microgravity on Early Embryonic Development and Embryonic Stem Cell Differentiation: Phenotypic Characterization and Potential Mechanisms.

Authors:  Feng Li; Ying Ye; Xiaohua Lei; Wensheng Zhang
Journal:  Front Cell Dev Biol       Date:  2021-12-02

5.  Development of a new device for manipulating frozen mouse 2-cell embryos on the International Space Station.

Authors:  Sayaka Wakayama; Mariko Soejima; Yasuyuki Kikuchi; Erika Hayashi; Natsuki Ushigome; Ayumi Hasegawa; Keiji Mochida; Tomomi Suzuki; Chiaki Yamazaki; Toru Shimazu; Hiromi Sano; Masumi Umehara; Hitomi Matsunari; Atsuo Ogura; Hiroshi Nagashima; Teruhiko Wakayama
Journal:  PLoS One       Date:  2022-10-07       Impact factor: 3.752

6.  Detrimental effects of microgravity on mouse preimplantation development in vitro.

Authors:  Sayaka Wakayama; Yumi Kawahara; Chong Li; Kazuo Yamagata; Louis Yuge; Teruhiko Wakayama
Journal:  PLoS One       Date:  2009-08-25       Impact factor: 3.240

7.  Evaluating the long-term effect of space radiation on the reproductive normality of mammalian sperm preserved on the International Space Station.

Authors:  Sayaka Wakayama; Daiyu Ito; Yuko Kamada; Toru Shimazu; Tomomi Suzuki; Aiko Nagamatsu; Ryoko Araki; Takahiro Ishikawa; Satoshi Kamimura; Naoki Hirose; Kousuke Kazama; Li Yang; Rei Inoue; Yasuyuki Kikuchi; Erika Hayashi; Rina Emura; Ren Watanabe; Hiroaki Nagatomo; Hiromi Suzuki; Tohru Yamamori; Motoki N Tada; Ikuko Osada; Masumi Umehara; Hiromi Sano; Haruo Kasahara; Akira Higashibata; Sachiko Yano; Masumi Abe; Satoshi Kishigami; Takashi Kohda; Masatoshi Ooga; Teruhiko Wakayama
Journal:  Sci Adv       Date:  2021-06-11       Impact factor: 14.136

  7 in total

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