Literature DB >> 11537109

Preliminary medical results of the Mir year-long mission.

A I Grigoriev1, S A Bugrov, V V Bogomolov, A D Egorov, I B Kozlovskaya, I D Pestov, V V Polyakov, I K Tarasov.   

Abstract

The basic goal of medical investigations during and after the 366-day mission was to accumulate data about physiological responses to such a long exposure to microgravity. In flight, cardiovascular and other systems were examined in detail and the efficacy of countermeasures used was assessed. After flight, physiological systems were also followed very carefully. According to the preliminary data, the medical results obtained during and after flight give evidence that man can well adapt to a year-long space flight, maintaining good health and adequate work capacity. The readaptation process was very similar to that observed after shorter flights (6-11 months). As compared to former flights, no new or qualitatively different changes in the vital systems of the body were seen. The observations indicate that the duration of manned space missions can be further increased.

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Year:  1991        PMID: 11537109     DOI: 10.1016/0094-5765(91)90092-j

Source DB:  PubMed          Journal:  Acta Astronaut        ISSN: 0094-5765            Impact factor:   2.413


  6 in total

Review 1.  Medications in Space: In Search of a Pharmacologist's Guide to the Galaxy.

Authors:  Sara Eyal; Hartmut Derendorf
Journal:  Pharm Res       Date:  2019-08-14       Impact factor: 4.200

Review 2.  Water and electrolyte studies during long-term missions onboard the space stations SALYUT and MIR.

Authors:  A I Grigoriev; B V Morukov; D V Vorobiev
Journal:  Clin Investig       Date:  1994-02

Review 3.  The Future of Personalized Medicine in Space: From Observations to Countermeasures.

Authors:  Elizabeth Pavez Loriè; Sarah Baatout; Alexander Choukér; Judith-Irina Buchheim; Bjorn Baselet; Cinzia Dello Russo; Virginia Wotring; Monica Monici; Lucia Morbidelli; Dimitri Gagliardi; Julia Caroline Stingl; Leonardo Surdo; Vincent Lai Ming Yip
Journal:  Front Bioeng Biotechnol       Date:  2021-12-13

Review 4.  Physiological adaptations affecting drug pharmacokinetics in space: what do we really know? A critical review of the literature.

Authors:  Cinzia Dello Russo; Tiziano Bandiera; Monica Monici; Leonardo Surdo; Vincent Lai Ming Yip; Virginia Wotring; Lucia Morbidelli
Journal:  Br J Pharmacol       Date:  2022-03-15       Impact factor: 9.473

5.  Blood flow-restricted exercise in space.

Authors:  Meghan Everett; Jessica M Scott; Lori Ploutz-Snyder; Kyle J Hackney
Journal:  Extrem Physiol Med       Date:  2012-12-01

Review 6.  Translating current biomedical therapies for long duration, deep space missions.

Authors:  Sonia Iosim; Matthew MacKay; Craig Westover; Christopher E Mason
Journal:  Precis Clin Med       Date:  2019-11-15
  6 in total

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