Literature DB >> 11536610

Oligomerization of deoxynucleoside-bisphosphate dimers: template and linkage specificity.

J Visscher1, R van der Woerd, C G Bakker, A W Schwartz.   

Abstract

Evidence is presented that a poly(U) template selectively favors the oligomerization of the activated, 3'-5' pyrophosphate-linked dimer pdAppdAp, in comparison with the 3'-3' and 5'-5' linked dimers. In the absence of poly(U), the 5'-5' linked dimer is the most reactive, and chains are formed which are more than 60 monomer units in length.

Entities:  

Keywords:  NASA Discipline Exobiology; Non-NASA Center

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Year:  1989        PMID： 11536610     DOI： 10.1007/bf01808283

Source DB:  PubMed          Journal:  Orig Life Evol Biosph        ISSN： 0169-6149            Impact factor:   1.950


  3 in total

1.  Template-directed synthesis of novel, nucleic acid-like structures.

Authors:  A W Schwartz; L E Orgel
Journal:  Science       Date:  1985-05-03       Impact factor: 47.728

2.  Template-directed synthesis of acyclic oligonucleotide analogues.

Authors:  J Visscher; A W Schwartz
Journal:  J Mol Evol       Date:  1988 Dec-1989 Feb       Impact factor: 2.395

3.  Nucleic acid-like structures. II. Polynucleotide analogues as possible primitive precursors of nucleic acids.

Authors:  A W Schwartz; J Visscher; C G Bakker; J Niessen
Journal:  Orig Life Evol Biosph       Date:  1987       Impact factor: 1.950
  3 in total
  2 in total

1.  Oligomerization of cytosine-containing nucleotide analogs in aqueous solution.

Authors:  J Visscher; A W Schwartz
Journal:  J Mol Evol       Date:  1990-01       Impact factor: 2.395

2.  Oligomerizations of deoxyadenosine bis-phosphates and of their 3'-5', 3'-3', and 5'-5' dimers: effects of a pyrophosphate-linked, poly(T) analog.

Authors:  J Visscher; C G Bakker; A W Schwartz
Journal:  Orig Life Evol Biosph       Date:  1990       Impact factor: 1.950
  2 in total

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