Literature DB >> 11536281

Magnetic field exposure and behavioral monitoring system.

A W Thomas1, D J Drost, F S Prato.   

Abstract

To maximize the availability and usefulness of a small magnetic field exposure laboratory, we designed a magnetic field exposure system that has been used to test human subjects, caged or confined animals, and cell cultures. The magnetic field exposure system consists of three orthogonal pairs of coils 2 m square x 1 m separation, 1.751 m x 0.875 m separation, and 1.5 m x 0.75 m separation. Each coil consisted of ten turns of insulated 8 gauge stranded copper conductor. Each of the pairs were driven by a constant-current amplifier via digital to analog (D/A) converter. A 9 pole zero-gain active Bessel low-pass filter (1 kHz corner frequency) before the amplifier input attenuated the expected high frequencies generated by the D/A conversion. The magnetic field was monitored with a 3D fluxgate magnetometer (0-3 kHz, +/- 1 mT) through an analog to digital converter. Behavioral monitoring utilized two monochrome video cameras (viewing the coil center vertically and horizontally), both of which could be video recorded and real-time digitally Moving Picture Experts Group (MPEG) encoded to CD-ROM. Human postural sway (standing balance) was monitored with a 3D forceplate mounted on the floor, connected to an analog to digital converter. Lighting was provided by 12 offset overhead dimmable fluorescent track lights and monitored using a digitally connected spectroradiometer. The dc resistance, inductance of each coil pair connected in series were 1.5 m coil (0.27 Omega, 1.2 mH), 1.75 m coil (0.32 Omega, 1.4 mH), and 2 m coil (0.38 Omega, 1.6 mH). The frequency response of the 1.5 m coil set was 500 Hz at +/- 463 microT, 1 kHz at +/- 232 microT, 150 micros rise time from -200 microT(pk) to + 200 microT(pk) (square wave) and is limited by the maximum voltage ( +/- 146 V) of the amplifier (Bessel filter bypassed). Copyright 2001 Wiley-Liss, Inc.

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Year:  2001        PMID: 11536281     DOI: 10.1002/bem.67

Source DB:  PubMed          Journal:  Bioelectromagnetics        ISSN: 0197-8462            Impact factor:   2.010


  1 in total

1.  Shielding, but not zeroing of the ambient magnetic field reduces stress-induced analgesia in mice.

Authors:  E Choleris; C Del Seppia; A W Thomas; P Luschi; G Ghione; G R Moran; F S Prato
Journal:  Proc Biol Sci       Date:  2002-01-22       Impact factor: 5.349

  1 in total

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