| Literature DB >> 1153620 |
Abstract
Rats were given dl-amphetamine 16 mg/kg twice daily for 15 days. Complete tolerance to the anorexigenic effect of amphetamine developed from day 7--11. A single injection of 16 mg/kg amphetamine was given to the amphetamine pretreated rats and to saline pretreated controls at different time-points after withdrawal, and their food intakes were compared. Signs of tolerance were present in 16 but not 20 days after withdrawal.Entities:
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Year: 1975 PMID： 1153620 DOI： 10.1007/bf00428823
Source DB: PubMed Journal: Psychopharmacologia