| Literature DB >> 11534901 |
S A Snyder1, T L Keith, S L Pierens, E M Snyder, J P Giesy.
Abstract
Bioconcentration of p-nonylphenol (NP) by fathead minnows was determined under laboratory conditions. Fish were exposed continuously for 42 days to 0.33, 0.93 and 2.36 microg NP/l in a flow-through system. NP was Soxhlet extracted from whole fish homogenates with dichloromethane (DCM). The resulting extract was concentrated and bulk lipids removed by gel permeation and silica-gel chromatography. Compounds were identified and quantified by reverse-phase high-pressure liquid chromatography (RP-HPLC) with fluorescence detection. Mass spectrometry was used for verification of peak assignments. Bioconcentration factors (BCFs) ranged from 245 to 380.Entities:
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Year: 2001 PMID： 11534901 DOI： 10.1016/s0045-6535(00)00524-5
Source DB: PubMed Journal: Chemosphere ISSN： 0045-6535 Impact factor: 7.086