Literature DB >> 11534346

Analgesic, diuretic, and anti-inflammatory principle from Scoparia dulcis.

M Ahmed1, H A Shikha, S K Sadhu, M T Rahman, B K Datta.   

Abstract

Scoparinol, a diterpene, isolated from Scoparia dulcis showed significant analgesic (p < 0.001) and anti-inflammatory activity (p < 0.01) in animals. A sedative action of scoparinol was demonstrated by a marked potentiation of pentobarbital-induced sedation with a significant effect on both onset and duration of sleep (p < 0.05). Measurement of urine volume after administration of scoparinol indicated its significant diuretic action.

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Year:  2001        PMID: 11534346

Source DB:  PubMed          Journal:  Pharmazie        ISSN: 0031-7144            Impact factor:   1.267


  17 in total

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