Literature DB >> 11533771

Consanguinity, fertility, reproductive wastage, infant mortality and congenital malformations in Jordan.

S A Khoury1, D F Massad.   

Abstract

OBJECTIVES: Consanguinity is a wide spread practice in Jordan. The objective of this study is to explore the health effects of consanguinity, in particular fertility, reproductive wastage, infant mortality and congenital malformations.
METHODS: A stratified 2 stage cluster sample of 1867 married couples, representative of all population groups and all geographic locations of Jordan were randomly selected. A questionnaire was specially designed to explore each of the objectives set for the study and was field tested. A group of field workers were thoroughly trained on the implementation of this instrument. All 1867 couples were interviewed by these field workers and completed questionnaires were reviewed before data entry. Data analysis was carried out using SPSSX statistical package. Significance tests were performed wherever appropriate.
RESULTS: The study showed that fertility, as measured by the number of pregnancies, taking into consideration marriage duration, was not affected by consanguinity. Twin pregnancies and abortions did not show any significant difference between consanguineous and non-consanguineous marriages. Consanguineous marriages showed significantly higher rates of still births and infant mortality in general. Within the consanguineous group, female infant mortality rates were significantly higher than those of males. Congenital malformations as reported by mothers of consanguineous marriages were significantly higher than those reported by mothers of non-consanguineous marriages.
CONCLUSION: This study showed that consanguinity has a detrimental effect on many aspects of reproductive health.

Entities:  

Mesh:

Year:  2000        PMID: 11533771

Source DB:  PubMed          Journal:  Saudi Med J        ISSN: 0379-5284            Impact factor:   1.484


  8 in total

1.  Homozygous mutations in LPIN2 are responsible for the syndrome of chronic recurrent multifocal osteomyelitis and congenital dyserythropoietic anaemia (Majeed syndrome).

Authors:  P J Ferguson; S Chen; M K Tayeh; L Ochoa; S M Leal; A Pelet; A Munnich; S Lyonnet; H A Majeed; H El-Shanti
Journal:  J Med Genet       Date:  2005-07       Impact factor: 6.318

2.  Contrasting children and women's health and the determinants of health in a small-sized city.

Authors:  Erhan Eser; Gönül Dinç; Ahmet Murat Oral; Cemil Ozcan
Journal:  J Urban Health       Date:  2005-09-29       Impact factor: 3.671

3.  Developing and evaluating a culturally appropriate genetic service for consanguineous South Asian families.

Authors:  Nasaim Khan; John Benson; Rhona Macleod; Helen Kingston
Journal:  J Community Genet       Date:  2010-08-20

4.  Is consanguinity prevalence decreasing in Saudis?: A study in two generations.

Authors:  Arjumand Sultan Warsy; May Hamad Al-Jaser; Abeer Albdass; Sooad Al-Daihan; Mohammad Alanazi
Journal:  Afr Health Sci       Date:  2014-06       Impact factor: 0.927

5.  Consanguinity and adverse pregnancy outcomes: the north of Jordan experience.

Authors:  Basil R Obeidat; Yousef S Khader; Zouhair O Amarin; Mohammad Kassawneh; Mousa Al Omari
Journal:  Matern Child Health J       Date:  2008-11-04

6.  Consanguinity and birth defects in the jerusalem perinatal study cohort.

Authors:  S Harlap; K Kleinhaus; M C Perrin; R Calderon-Margalit; O Paltiel; L Deutsch; O Manor; E Tiram; R Yanetz; Y Friedlander
Journal:  Hum Hered       Date:  2008-05-20       Impact factor: 0.444

7.  Interplay of socio-economic factors, consanguinity, fertility, and offspring mortality in Monastir, Tunisia.

Authors:  Emna Kerkeni; Kamel Monastiri; Besma Saket; Mohamed Neji Guediche; Hassen Ben Cheikh
Journal:  Croat Med J       Date:  2007-10       Impact factor: 1.351

8.  Consanguinity and reproductive health among Arabs.

Authors:  Ghazi O Tadmouri; Pratibha Nair; Tasneem Obeid; Mahmoud T Al Ali; Najib Al Khaja; Hanan A Hamamy
Journal:  Reprod Health       Date:  2009-10-08       Impact factor: 3.223

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.