Literature DB >> 11530357

Genetic variability following selection of Haemonchus contortus with anthelmintics.

R Prichard1.   

Abstract

Genetic diversity in nematodes leads to variation in response to anthelmintics. Haemonchus contortus shows enormous genetic diversity, allowing anthelmintic resistance alleles to be rapidly selected. Anthelmintic resistance is now a widespread problem, especially in H. contortus. Here, I compare the genes involved in anthelmintic resistance in H. contortus with those that confer susceptibility or resistance on the free living nematode Caenorhabditis elegans. I also discuss the latest knowledge of genes associated with resistance to benzimidazoles, levamisole and the macrocyclic lactones and the need for DNA markers for anthelmintic resistance.

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Year:  2001        PMID: 11530357     DOI: 10.1016/s1471-4922(01)01983-3

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN: 1471-4922


  64 in total

1.  Spatial parasite transmission, drug resistance, and the spread of rare genes.

Authors:  S J Cornell; V S Isham; G Smith; B T Grenfell
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-27       Impact factor: 11.205

Review 2.  Onchocerciasis.

Authors:  Achim Hoerauf; Dietrich W Büttner; Ohene Adjei; Eric Pearlman
Journal:  BMJ       Date:  2003-01-25

3.  An assessment of benzimidazole resistance against caprine nematodes in Central India.

Authors:  A K Dixit; G Das; Pooja Dixit; A P Singh; N K Kumbhakar; M Sankar; R L Sharma
Journal:  Trop Anim Health Prod       Date:  2017-07-17       Impact factor: 1.559

4.  Liver fluke β-tubulin isotype 2 binds albendazole and is thus a probable target of this drug.

Authors:  Emma Chambers; Louise A Ryan; Elizabeth M Hoey; Alan Trudgett; Neil V McFerran; Ian Fairweather; David J Timson
Journal:  Parasitol Res       Date:  2010-07-31       Impact factor: 2.289

5.  Expression of recombinant beta-tubulin alleles from Cylicocyclus nassatus (Cyathostominae).

Authors:  William J Blackhall; Michaela Drogemuller; Thomas Schnieder; Georg von Samson-Himmelstjerna
Journal:  Parasitol Res       Date:  2006-11       Impact factor: 2.289

6.  Population genetics of benzimidazole-resistant Haemonchus contortus and Haemonchus placei from buffalo and cattle: implications for the emergence and spread of resistance mutations.

Authors:  Qasim Ali; Imran Rashid; Muhammad Zubair Shabbir; Kashif Shahzad; Kamran Ashraf; Neil D Sargison; Umer Chaudhry
Journal:  Parasitol Res       Date:  2018-08-24       Impact factor: 2.289

7.  Identification of two beta-tubulin isotypes of Clonorchis sinensis.

Authors:  Shunyu Li; Sung-Jong Hong; Min-Ho Choi; Sung-Tae Hong
Journal:  Parasitol Res       Date:  2009-06-10       Impact factor: 2.289

8.  Meiosis-specific failure of cell cycle progression in fission yeast by mutation of a conserved beta-tubulin residue.

Authors:  Janet L Paluh; Alison N Killilea; H William Detrich; Kenneth H Downing
Journal:  Mol Biol Cell       Date:  2003-12-02       Impact factor: 4.138

9.  Purifying selection and demographic expansion affect sequence diversity of the ligand-binding domain of a glutamate-gated chloride channel gene of Haemonchus placei.

Authors:  Ted H M Mes
Journal:  J Mol Evol       Date:  2004-04       Impact factor: 2.395

10.  Determination of genomic DNA sequences for beta-tubulin isotype 1 from multiple species of cyathostomin and detection of resistance alleles in third-stage larvae from horses with naturally acquired infections.

Authors:  Sarah L Lake; Jacqueline B Matthews; Ray M Kaplan; Jane E Hodgkinson
Journal:  Parasit Vectors       Date:  2009-09-25       Impact factor: 3.876

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