Literature DB >> 11529775

Generating diversity in difluoromethyl ketone derivatives.

G A DeBoos1, J J Fullbrook, J M Percy.   

Abstract

[reaction: see text]. Two consecutive palladium-catalyzed coupling reactions from a readily available difluoroenol stannane set the stage for the synthesis of a range of difluoro- and halodifluoromethyl ketones upon a variable aryl template.

Entities:  

Year:  2001        PMID: 11529775     DOI: 10.1021/ol010135p

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  4 in total

1.  Synthesis of α-halo-α,α-difluoromethyl ketones by a trifluoroacetate release/halogenation protocol.

Authors:  Jinu P John; David A Colby
Journal:  J Org Chem       Date:  2011-10-13       Impact factor: 4.354

2.  Optimized Synthesis of a Pentafluoro-gem-diol and Conversion to a CF2Br-Glucopyranose through Trifluoroacetate-Release and Halogenation.

Authors:  Robert A Hazlitt; Jinu P John; Que-Lynn Tran; David A Colby
Journal:  Tetrahedron Lett       Date:  2016-03-19       Impact factor: 2.415

3.  Chemoselectivity in the Kosugi-Migita-Stille coupling of bromophenyl triflates and bromo-nitrophenyl triflates with (ethenyl)tributyltin.

Authors:  Nurul N Ansari; Matthew M Cummings; Björn C G Söderberg
Journal:  Tetrahedron       Date:  2018-04-10       Impact factor: 2.457

4.  Consecutive cross-coupling reactions of 2,2-difluoro-1-iodoethenyl tosylate with boronic acids: efficient synthesis of 1,1-diaryl-2,2-difluoroethenes.

Authors:  Ju Hee Kim; Su Jeong Choi; In Howa Jeong
Journal:  Beilstein J Org Chem       Date:  2013-11-14       Impact factor: 2.883

  4 in total

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