Literature DB >> 11529771

Synthesis of (+)-galiellalactone. Absolute configuration of galiellalactone.

M Johansson1, O Sterner.   

Abstract

[reaction: see text]. (+)-Galiellalactone was synthesized starting from (R)-(+)-pulegone. Natural and synthetic galiellalactone have opposite optical rotations, demonstrating that the structure of the natural product is 1a.

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Year:  2001        PMID: 11529771     DOI: 10.1021/ol016286+

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  5 in total

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Authors:  Andrea A Stierle; Donald B Stierle; Teri Girtsman
Journal:  J Nat Prod       Date:  2012-02-01       Impact factor: 4.050

2.  Galiellalactone is a direct inhibitor of the transcription factor STAT3 in prostate cancer cells.

Authors:  Nicholas Don-Doncow; Zilma Escobar; Martin Johansson; Sven Kjellström; Victor Garcia; Eduardo Munoz; Olov Sterner; Anders Bjartell; Rebecka Hellsten
Journal:  J Biol Chem       Date:  2014-04-22       Impact factor: 5.157

Review 3.  Toward a Cancer Drug of Fungal Origin.

Authors:  Alexander Kornienko; Antonio Evidente; Maurizio Vurro; Véronique Mathieu; Alessio Cimmino; Marco Evidente; Willem A L van Otterlo; Ramesh Dasari; Florence Lefranc; Robert Kiss
Journal:  Med Res Rev       Date:  2015-04-08       Impact factor: 12.944

4.  Synthesis of 7-epineoptilocaulin, mirabilin B, and isoptilocaulin. A unified biosynthetic proposal for the ptilocaulin and batzelladine alkaloids. Synthesis and structure revision of netamines E and G.

Authors:  Min Yu; Susan S Pochapsky; Barry B Snider
Journal:  J Org Chem       Date:  2008-10-18       Impact factor: 4.354

5.  Galiellalactone induces cell cycle arrest and apoptosis through the ATM/ATR pathway in prostate cancer cells.

Authors:  Víctor García; Maribel Lara-Chica; Irene Cantarero; Olov Sterner; Marco A Calzado; Eduardo Muñoz
Journal:  Oncotarget       Date:  2016-01-26
  5 in total

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