| Literature DB >> 11527741 |
C S Jeung1, C H Kim, K Min, S W Suh, J Suh.
Abstract
Reactivity of the Co(III) complex of cyclen (CoCyc) in the hydrolytic cleavage of supercoiled pUC18 DNA leading to the formation of the corresponding open circular form was enhanced by >200 times upon attachment of CoCyc to cross-linked polystyrenes. Thus, half-lives as short as 40 min were achieved by the resin-based CoCyc in cleavage of the supercoiled DNA at 4 degrees C.Entities:
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Year: 2001 PMID： 11527741 DOI： 10.1016/s0960-894x(01)00439-5
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823