Literature DB >> 11527584

Protection of radiation-induced protein damage by curcumin.

S Kapoor1, K I Priyadarsini.   

Abstract

Free radical reactions of lysozyme (Lz), tryptophan and disulfides were studied with curcumin, a lipid-soluble antioxidant from turmeric, in aqueous solution using a pulse radiolysis technique. The binding of curcumin with lysozyme was confirmed using absorption, fluorescence and stopped-flow techniques. The free radicals of curcumin generated after repairing radicals of disulfides, lysozyme and tryptophan absorb at 500-510 nm. Implication of this in evaluating the antioxidant behavior of curcumin in protecting proteins is discussed.

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Year:  2001        PMID： 11527584     DOI： 10.1016/s0301-4622(01)00188-0

Source DB:  PubMed          Journal:  Biophys Chem        ISSN： 0301-4622            Impact factor:   2.352


  8 in total

1.  In vivo study on the effects of curcumin on the expression profiles of anti-tumour genes (VEGF, CyclinD1 and CDK4) in liver of rats injected with DEN.

Authors:  Chu Zhu Huang; Wei Zhe Huang; Ge Zhang; Dan Ling Tang
Journal:  Mol Biol Rep       Date:  2013-10-11       Impact factor: 2.316

Review 2.  Multitargeting by curcumin as revealed by molecular interaction studies.

Authors:  Subash C Gupta; Sahdeo Prasad; Ji Hye Kim; Sridevi Patchva; Lauren J Webb; Indira K Priyadarsini; Bharat B Aggarwal
Journal:  Nat Prod Rep       Date:  2011-10-06       Impact factor: 13.423

3.  Recent advances in the investigation of curcuminoids.

Authors:  Hideji Itokawa; Qian Shi; Toshiyuki Akiyama; Susan L Morris-Natschke; Kuo-Hsiung Lee
Journal:  Chin Med       Date:  2008-09-17       Impact factor: 5.455

4.  A microliter-scale high-throughput screening system with quantum-dot nanoprobes for amyloid-β aggregation inhibitors.

Authors:  Yukako Ishigaki; Hiroyuki Tanaka; Hiroaki Akama; Toshiki Ogara; Koji Uwai; Kiyotaka Tokuraku
Journal:  PLoS One       Date:  2013-08-26       Impact factor: 3.240

5.  Curcumin mitigates accelerated aging after irradiation in Drosophila by reducing oxidative stress.

Authors:  Ki Moon Seong; Mira Yu; Kyu-Sun Lee; Sunhoo Park; Young Woo Jin; Kyung-Jin Min
Journal:  Biomed Res Int       Date:  2015-03-01       Impact factor: 3.411

6.  Disturbed sensorimotor and electrophysiological patterns in lead intoxicated rats during development are restored by curcumin I.

Authors:  Hind Benammi; Hasna Erazi; Omar El Hiba; Laurent Vinay; Hélène Bras; Jean-Charles Viemari; Halima Gamrani
Journal:  PLoS One       Date:  2017-03-07       Impact factor: 3.240

7.  Chitosan-alginate sponge: preparation and application in curcumin delivery for dermal wound healing in rat.

Authors:  Mei Dai; Xiuling Zheng; Xu Xu; Xiangye Kong; Xingyi Li; Gang Guo; Feng Luo; Xia Zhao; Yu Quan Wei; Zhiyong Qian
Journal:  J Biomed Biotechnol       Date:  2009-11-11

8.  Turmeric (curcumin) remedies gastroprotective action.

Authors:  Santosh Kumar Yadav; Ajit Kumar Sah; Rajesh Kumar Jha; Phoolgen Sah; Dev Kumar Shah
Journal:  Pharmacogn Rev       Date:  2013-01
  8 in total

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