Literature DB >> 11527238

Amatoxin poisoning from ingestion of Japanese Galerina mushrooms.

H Kaneko1, T Tomomasa, Y Inoue, F Kunimoto, T Fukusato, S Muraoka, K Gonmori, T Matsumoto, A Morikawa.   

Abstract

BACKGROUND: Although some Japanese Galerina species poisonings manifest as gastrointestinal symptoms followed by late-onset hepatorenal failure (phalloides syndrome), the toxin responsible for this has not been determined. CASE REPORT: We report a 6-year-old boy who developed characteristic cholera-like diarrhea and late-onset severe hepatic deterioration after eating mushrooms, later identified as a Galerina species, most likely Galerina fasciculata. A residual mushroom revealed alpha-amanitin. This account is the first known reported case of poisoning by Japanese Galerina species where an amatoxin was demonstrated to be responsible for the toxicity.

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Year:  2001        PMID: 11527238     DOI: 10.1081/clt-100105164

Source DB:  PubMed          Journal:  J Toxicol Clin Toxicol        ISSN: 0731-3810


  4 in total

1.  Ribosomal biosynthesis of α-amanitin in Galerina marginata.

Authors:  Hong Luo; Heather E Hallen-Adams; John S Scott-Craig; Jonathan D Walton
Journal:  Fungal Genet Biol       Date:  2011-12-21       Impact factor: 3.495

2.  Peptide macrocyclization catalyzed by a prolyl oligopeptidase involved in α-amanitin biosynthesis.

Authors:  Hong Luo; Sung-Yong Hong; R Michael Sgambelluri; Evan Angelos; Xuan Li; Jonathan D Walton
Journal:  Chem Biol       Date:  2014-12-04

3.  Phylogenetic analysis of the distribution of deadly amatoxins among the little brown mushrooms of the genus Galerina.

Authors:  Brandon Landry; Jeannette Whitton; Anna L Bazzicalupo; Oldriska Ceska; Mary L Berbee
Journal:  PLoS One       Date:  2021-02-10       Impact factor: 3.240

Review 4.  Human Poisoning from Poisonous Higher Fungi: Focus on Analytical Toxicology and Case Reports in Forensic Toxicology.

Authors:  Estelle Flament; Jérôme Guitton; Jean-Michel Gaulier; Yvan Gaillard
Journal:  Pharmaceuticals (Basel)       Date:  2020-12-11
  4 in total

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