Literature DB >> 11526047

Biotransformation of malachite green by the fungus Cunninghamella elegans.

C J Cha1, D R Doerge, C E Cerniglia.   

Abstract

The filamentous fungus Cunninghamella elegans ATCC 36112 metabolized the triphenylmethane dye malachite green with a first-order rate constant of 0.029 micromol x h(-1) (mg of cells)(-1). Malachite green was enzymatically reduced to leucomalachite green and also converted to N-demethylated and N-oxidized metabolites, including primary and secondary arylamines. Inhibition studies suggested that the cytochrome P450 system mediated both the reduction and the N-demethylation reactions.

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Year:  2001        PMID: 11526047      PMCID: PMC93171          DOI: 10.1128/AEM.67.9.4358-4360.2001

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN: 0099-2240            Impact factor:   4.792


  19 in total

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