| Literature DB >> 11526047 |
C J Cha1, D R Doerge, C E Cerniglia.
Abstract
The filamentous fungus Cunninghamella elegans ATCC 36112 metabolized the triphenylmethane dye malachite green with a first-order rate constant of 0.029 micromol x h(-1) (mg of cells)(-1). Malachite green was enzymatically reduced to leucomalachite green and also converted to N-demethylated and N-oxidized metabolites, including primary and secondary arylamines. Inhibition studies suggested that the cytochrome P450 system mediated both the reduction and the N-demethylation reactions.Entities:
Mesh:
Substances:
Year: 2001 PMID: 11526047 PMCID: PMC93171 DOI: 10.1128/AEM.67.9.4358-4360.2001
Source DB: PubMed Journal: Appl Environ Microbiol ISSN: 0099-2240 Impact factor: 4.792