Literature DB >> 11525784

The selective sigma(1) receptor agonist, 1-(3,4-dimethoxyphenethyl)-4-(phenylpropyl)piperazine (SA4503), blocks the acquisition of the conditioned place preference response to (-)-nicotine in rats.

B Horan1, E L Gardner, S L Dewey, J D Brodie, C R Ashby.   

Abstract

We examined the effect of the sigma(1) receptor agonist, 1-(3,4-dimethoxyphenethyl)-4-(phenylpropyl)piperazine (SA4503), on the acquisition of the conditioned place preference response to subcutaneously administered (-)-nicotine in rats. (-)-Nicotine, but not SA4503 or vehicle, produced a significant conditioned place preference response. Pretreatment of animals with either 1 or 3 mg/kg of SA4503 significantly attenuated the conditioned place preference response to (-)-nicotine.

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Year:  2001        PMID： 11525784     DOI： 10.1016/s0014-2999(01)01229-8

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  12 in total

1.  The sigma receptor agonist SA4503 both attenuates and enhances the effects of methamphetamine.

Authors:  Kelli R Rodvelt; Clark E Oelrichs; Lucas R Blount; Kuo-Hsien Fan; Susan Z Lever; John R Lever; Dennis K Miller
Journal:  Drug Alcohol Depend       Date:  2011-02-01       Impact factor: 4.492

2.  The selective dopamine D3 receptor antagonist SB-277011A reduces nicotine-enhanced brain reward and nicotine-paired environmental cue functions.

Authors:  Arlene C Pak; Charles R Ashby; Christian A Heidbreder; Maria Pilla; Jeremy Gilbert; Zheng-Xiong Xi; Eliot L Gardner
Journal:  Int J Neuropsychopharmacol       Date:  2006-08-31       Impact factor: 5.176

3.  Targeting sigma receptors: novel medication development for drug abuse and addiction.

Authors:  Rae R Matsumoto
Journal:  Expert Rev Clin Pharmacol       Date:  2009-07       Impact factor: 5.045

4.  Nicotine induces conditioned place preferences over a large range of doses in rats.

Authors:  Bernard Le Foll; Steven R Goldberg
Journal:  Psychopharmacology (Berl)       Date:  2004-11-18       Impact factor: 4.530

5.  Repeated nicotine treatment in rats with high versus low rearing activity: analyses of behavioural sensitisation and place preference.

Authors:  Cornelius R Pawlak; Rainer K W Schwarting
Journal:  Psychopharmacology (Berl)       Date:  2004-11-17       Impact factor: 4.530

6.  SA 4503 attenuates cocaine-induced hyperactivity and enhances methamphetamine substitution for a cocaine discriminative stimulus.

Authors:  Kelli R Rodvelt; Susan Z Lever; John R Lever; Lucas R Blount; Kuo-Hsien Fan; Dennis K Miller
Journal:  Pharmacol Biochem Behav       Date:  2010-11-27       Impact factor: 3.533

7.  dextro-Morphine attenuates the morphine-produced conditioned place preference via the sigma(1) receptor activation in the rat.

Authors:  Hsiang-en Wu; Emma T Schwasinger; Maia Terashvili; Leon F Tseng
Journal:  Eur J Pharmacol       Date:  2007-02-08       Impact factor: 4.432

Review 8.  Constitutional mechanisms of vulnerability and resilience to nicotine dependence.

Authors:  N Hiroi; D Scott
Journal:  Mol Psychiatry       Date:  2009-02-24       Impact factor: 15.992

9.  Intravenous nicotine conditions a place preference in rats using an unbiased design.

Authors:  Jamie L Wilkinson; Rick A Bevins
Journal:  Pharmacol Biochem Behav       Date:  2007-09-01       Impact factor: 3.533

10.  The sigma receptor ligand N-phenylpropyl-N'-(4-methoxyphenethyl)3piperazine (YZ-067) enhances the cocaine conditioned-rewarding properties while inhibiting the development of sensitization of cocaine in mice.

Authors:  Melissa A Tapia; Andrew S Sage; Emma I Fullerton; Jessica M Judd; Paige C Hildebrant; Matthew J Will; Susan Z Lever; John R Lever; Dennis K Miller
Journal:  Psychopharmacology (Berl)       Date:  2019-12-10       Impact factor: 4.530
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