Literature DB >> 115254

Inhibition of diamine oxidase by antihistaminic agents and related drugs.

A Finazzi-Agrò, G Floris, M B Fadda, C Crifò.   

Abstract

Various drugs were tested as inhibitors of diamine oxidase on the basis of chemical relationships to the enzyme substrates. It was found that serotonine tryptamine and phenformin are good competitive inhibitors while cimetidine and pheniprazine are non-competitive inhibitors. Other antihistaminic drugs like promethazine are less powerful inhibitors.

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Year:  1979        PMID: 115254     DOI: 10.1007/bf01966695

Source DB:  PubMed          Journal:  Agents Actions        ISSN: 0065-4299


  15 in total

1.  The determination of enzyme inhibitor constants.

Authors:  M DIXON
Journal:  Biochem J       Date:  1953-08       Impact factor: 3.857

Review 2.  Polyamines in rapid growth and cancer.

Authors:  J Jänne; H Pösö; A Raina
Journal:  Biochim Biophys Acta       Date:  1978-04-06

3.  Kinetics of the interaction between pig-plasma benzylamine oxidase and hydrazine derivatives.

Authors:  A Lindström; B Olsson; G Pettersson
Journal:  Eur J Biochem       Date:  1974-02-15

Review 4.  Histaminase and related amine oxidases.

Authors:  F Buffoni
Journal:  Pharmacol Rev       Date:  1966-12       Impact factor: 25.468

5.  The cross-linking of collagen and elastin: enzymatic conversion of lysine in peptide linkage to alpha-aminoadipic-delta-semialdehyde (allysine) by an extract from bone.

Authors:  S R Pinnell; G R Martin
Journal:  Proc Natl Acad Sci U S A       Date:  1968-10       Impact factor: 11.205

6.  Monoamine oxidase inhibitors and other drugs as inhibitors of diamine oxidase from human placenta and pig kidney.

Authors:  M J Crabbe; W G Bardsley
Journal:  Biochem Pharmacol       Date:  1974-11-01       Impact factor: 5.858

7.  On the active site of diamine oxidase: kinetic studies.

Authors:  M T Costa; G Rotilio; A F Agró; M P Vallogini; B Mondovì
Journal:  Arch Biochem Biophys       Date:  1971-11       Impact factor: 4.013

8.  4-aminobutyrate in mammalian putrescine catabolism.

Authors:  N Seiler; B Eichentopf
Journal:  Biochem J       Date:  1975-11       Impact factor: 3.857

9.  The action of plasma amine oxidase on beta-haloamines. Evidence for proton abstraction in the oxidative reaction.

Authors:  R Neumann; R Hevey; R H Abeles
Journal:  J Biol Chem       Date:  1975-08-25       Impact factor: 5.157

10.  On the nature of chromophore in pig kidney diamine oxidase.

Authors:  A F Agrò; P Guerrieri; M T Costa; B Mondovì
Journal:  Eur J Biochem       Date:  1977-04-15
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  2 in total

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