Literature DB >> 11524943

[Major mRNP proteins in the structural organization and function of mRNA in eukaryotic cells].

L P Ovchinnikov1, M A Skabkin, P V Ruzanov, V M Evdokimova.   

Abstract

The properties of two universal major proteins of cytoplasmic mRNP, p50 and the poly(A)-binding protein (PABP), are summarized. Their roles in formation of polyribosomal and free inactive mRNP are considered, with the focus on the authors' studies of p50. The parts these mRNP proteins play in translation regulation, stability, and localization of mRNA are described, and the the possible mechanisms of their function are discussed.

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Year:  2001        PMID: 11524943

Source DB:  PubMed          Journal:  Mol Biol (Mosk)        ISSN: 0026-8984


  5 in total

1.  P50/YB-1, a major protein of cytoplasmic mRNPs, regulates its own synthesis.

Authors:  O V Skabkina; M A Skabkin; D N Lyabin; L P Ovchinnikov
Journal:  Dokl Biochem Biophys       Date:  2004 Mar-Apr       Impact factor: 0.788

2.  Structural organization of mRNA complexes with major core mRNP protein YB-1.

Authors:  Maxim A Skabkin; Olga I Kiselyova; Konstantin G Chernov; Alexey V Sorokin; Evgeniy V Dubrovin; Igor V Yaminsky; Victor D Vasiliev; Lev P Ovchinnikov
Journal:  Nucleic Acids Res       Date:  2004-10-19       Impact factor: 16.971

3.  YB-1 autoregulates translation of its own mRNA at or prior to the step of 40S ribosomal subunit joining.

Authors:  Olga V Skabkina; Dmitry N Lyabin; Maxim A Skabkin; Lev P Ovchinnikov
Journal:  Mol Cell Biol       Date:  2005-04       Impact factor: 4.272

4.  Identification of internal ribosome entry segment (IRES)-trans-acting factors for the Myc family of IRESs.

Authors:  Laura C Cobbold; Keith A Spriggs; Stephen J Haines; Helen C Dobbyn; Christopher Hayes; Cornelia H de Moor; Kathryn S Lilley; Martin Bushell; Anne E Willis
Journal:  Mol Cell Biol       Date:  2007-10-29       Impact factor: 4.272

Review 5.  Y-Box Binding Proteins in mRNP Assembly, Translation, and Stability Control.

Authors:  Daria Mordovkina; Dmitry N Lyabin; Egor A Smolin; Ekaterina M Sogorina; Lev P Ovchinnikov; Irina Eliseeva
Journal:  Biomolecules       Date:  2020-04-11
  5 in total

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