OBJECTIVE: To describe trends in the evolution of causes of death in a cohort of HIV-infected patients before and after the introduction of highly active antiretroviral treatment (HAART). METHODS: This descriptive study concerned all the patients of the Aquitaine cohort who died between 1995 and 1997. Causes of deaths were grouped into 13 'deaths due to an AIDS-defining underlying cause', and eight 'non AIDS' categories. Comparisons were performed between two comparable periods of 18 months, January 1995-June 1996 and July 1996-December 1997 to focus on changes introduced by the prescription of HAART in June 1996. RESULTS: Five hundred and thirty-two deaths were notified in 36 months for a total of 3687 patients. The comparison between causes of deaths before and after June 1996 showed a significant difference between the two periods with a decreasing proportion of AIDS causes of death, from 82.7% to 72.2% (p = 0.007). CONCLUSION: HAART treatment has reduced the number and percentage of deaths due to AIDS-related causes among persons who died with HIV infection in South-western France.
OBJECTIVE: To describe trends in the evolution of causes of death in a cohort of HIV-infectedpatients before and after the introduction of highly active antiretroviral treatment (HAART). METHODS: This descriptive study concerned all the patients of the Aquitaine cohort who died between 1995 and 1997. Causes of deaths were grouped into 13 'deaths due to an AIDS-defining underlying cause', and eight 'non AIDS' categories. Comparisons were performed between two comparable periods of 18 months, January 1995-June 1996 and July 1996-December 1997 to focus on changes introduced by the prescription of HAART in June 1996. RESULTS: Five hundred and thirty-two deaths were notified in 36 months for a total of 3687 patients. The comparison between causes of deaths before and after June 1996 showed a significant difference between the two periods with a decreasing proportion of AIDS causes of death, from 82.7% to 72.2% (p = 0.007). CONCLUSION: HAART treatment has reduced the number and percentage of deaths due to AIDS-related causes among persons who died with HIV infection in South-western France.
Authors: Y Mouton; S Alfandari; M Valette; F Cartier; P Dellamonica; G Humbert; J M Lang; P Massip; D Mechali; P Leclercq; J Modai; H Portier Journal: AIDS Date: 1997-10 Impact factor: 4.177
Authors: M Prins; I H Hernández Aguado; R P Brettle; J R Robertson; B Broers; N Carré; D J Goldberg; R Zangerle; R A Coutinho; A van den Hoek Journal: AIDS Date: 1997-11-15 Impact factor: 4.177
Authors: S Kravcik; N Hawley-Foss; G Victor; J B Angel; G E Garber; S Pagé; N Denommé; L O'Reilly; D W Cameron Journal: Arch Intern Med Date: 1997-10-13
Authors: Dawn K Smith; Lytt I Gardner; Ruby Phelps; Merle E Hamburger; Charles Carpenter; Robert S Klein; Ann Rompalo; Paula Schuman; Scott D Holmberg Journal: J Urban Health Date: 2003-12 Impact factor: 3.671