AIMS: To image the vitreoretinal interface and provide further information on the pathogenesis of idiopathic macular hole formation. METHODS: Prospective recruitment of 80 eyes of 41 consecutive patients referred with a diagnosis of idiopathic full thickness macular hole (FTMH) to a teaching hospital retinal clinic. Both eyes of each patient underwent optical coherence tomography (OCT) imaging with vertical and horizontal scans centred on the fovea. RESULTS: A total of 30 eyes had stage 2 or 3 FTMHs and, of these, 21 had persistent vitreofoveal attachment and associated prefoveal opacities. 18 prefoveal opacities were identified by Goldmann contact lens examination and confirmed on OCT examination. Three prefoveal opacities were identified only on OCT examination. 10 eyes had stage 4 FTMHs and four cases were identified in whom the OCT appearance was consistent with impending, aborted, or lamellar macular holes. CONCLUSIONS: The wide range in OCT appearance of macular holes and associated prefoveal opacities suggests that, in at least some cases, a significant amount of retinal tissue is torn from the foveal area during macular hole formation. OCT imaging provides additional information on macular hole pathogenesis and is valuable in the planning of surgical intervention.
AIMS: To image the vitreoretinal interface and provide further information on the pathogenesis of idiopathic macular hole formation. METHODS: Prospective recruitment of 80 eyes of 41 consecutive patients referred with a diagnosis of idiopathic full thickness macular hole (FTMH) to a teaching hospital retinal clinic. Both eyes of each patient underwent optical coherence tomography (OCT) imaging with vertical and horizontal scans centred on the fovea. RESULTS: A total of 30 eyes had stage 2 or 3 FTMHs and, of these, 21 had persistent vitreofoveal attachment and associated prefoveal opacities. 18 prefoveal opacities were identified by Goldmann contact lens examination and confirmed on OCT examination. Three prefoveal opacities were identified only on OCT examination. 10 eyes had stage 4 FTMHs and four cases were identified in whom the OCT appearance was consistent with impending, aborted, or lamellar macular holes. CONCLUSIONS: The wide range in OCT appearance of macular holes and associated prefoveal opacities suggests that, in at least some cases, a significant amount of retinal tissue is torn from the foveal area during macular hole formation. OCT imaging provides additional information on macular hole pathogenesis and is valuable in the planning of surgical intervention.
Authors: C A Toth; D G Narayan; S A Boppart; M R Hee; J G Fujimoto; R Birngruber; C P Cain; C D DiCarlo; W P Roach Journal: Arch Ophthalmol Date: 1997-11
Authors: Daniel M Stein; Gadi Wollstein; Hiroshi Ishikawa; Ellen Hertzmark; Robert J Noecker; Joel S Schuman Journal: Ophthalmology Date: 2006-06 Impact factor: 12.079
Authors: D M Stein; H Ishikawa; R Hariprasad; G Wollstein; R J Noecker; J G Fujimoto; J S Schuman Journal: Br J Ophthalmol Date: 2006-02 Impact factor: 4.638
Authors: P G Theodossiadis; V G Grigoropoulos; I Emfietzoglou; P Nikolaidis; I Vergados; M Apostolopoulos; G P Theodossiadis Journal: Graefes Arch Clin Exp Ophthalmol Date: 2008-09-03 Impact factor: 3.117
Authors: Andre J Witkin; Tony H Ko; James G Fujimoto; Joel S Schuman; Caroline R Baumal; Adam H Rogers; Elias Reichel; Jay S Duker Journal: Ophthalmology Date: 2006-03 Impact factor: 12.079